COVID-19 mRNA vaccines play a vital role in the fight against SARS-CoV-2 infection. However, lactating women have been largely excluded from most vaccine clinical trials. As a result, limited research ...
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A new communication medium between cardiomyocytes and fibroblasts
Myocardial fibrosis is major pathological outcome after myocardial ischemia/reperfusion (MI/R) injury and a major risk factor for heart failure. MI/R injury induces cardiomyocyte damage or even death, which in turn stimulates ...
Read More »FedEx for your cells: this biological delivery service could treat disease
Researchers want to know why cells produce tiny packages called vesicles — and whether these bundles could be used for therapy. Graça Raposo was a young postdoc in the Netherlands in 1996...
Read More »MDPI journal Cells announces special issue – “Stem-Cell-Derived Extracellular Vesicles as Cargo for Biomolecules including Lipids, Proteins or RNA”
In addition to the conventional molecular secretome, cells secrete large amounts of extracellular vesicles (EVs). EV is “the generic term for a particle naturally...
Read More »TurboID-EV – Proteomic Mapping of Recipient Cellular Proteins Proximal to Small Extracellular Vesicles
Extracellular vesicles (EVs), including exosomes, have been recognized as key mediators of intercellular communications through donor EV and recipient cell interaction. Until now, most studies...
Read More »Ion exchange chromatography as a simple and scalable method to isolate biologically active small extracellular vesicles from conditioned media
In the last few years, extracellular vesicles (EVs) have become of great interest due to their potential as biomarkers, drug delivery systems, and, in...
Read More »Rapid generation of functional nanovesicles from human trophectodermal cells for embryo attachment and outgrowth
Extracellular vesicles (EVs) are important mediators of embryo attachment and outgrowth critical for successful implantation. While EVs have garnered immense interest in their therapeutic potential in...
Read More »Extracellular vesicles as a potential source of tumor-derived DNA in advanced pancreatic cancer
Tumor-derived extracellular vesicles (EVs) are reported to contain nucleic acids, including DNA. Several studies have highlighted the potential of...
Read More »Placental exosomes as biomarkers for maternal diseases: current advances in isolation, characterization, and detection
Serving as the interface between fetal and maternal circulation, the placenta plays a critical role in fetal growth and development. Placental exosomes are small membrane-bound extracellular vesicles released...
Read More »Potential applications of tissue-specific EVs in targeted therapy and vaccinology
Many cell types secrete spherical membrane bodies classified as extracellular vesicles (EVs). EVs participate in intercellular communication and are...
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PhD position available – pathogen extracellular vesicles in RNA effector delivery
The research project offers to elucidate the molecular mechanisms and functions of extracellular vesicle-based small RNA transport from pathogens...
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PhD position available – gut microbiome-derived extracellular vesicles: role in gut health
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Postdoc position available – extracellular vesicle biology
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Featured Exosome Job – Laboratory Research Specialist
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Postdoc position available – extracellular vesicles as diagnostic risk-markers for non-alcoholic fatty liver disease in obesity
Industry News
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Coya Therapeutics Successfully Engineers Regulatory T Cell (Treg) Derived Exosomes with CTLA-4 Protein to Selectively Target Immune Cells with Potential to Deliver Targeted Therapies Across Multiple Diseases
Coya Therapeutics, a clinical-stage biotechnology company developing multiple therapeutic platforms intended to enhance Treg function, including biologics and cell therapies, announced...
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Biological Dynamics and The Pancreatic Cancer Early Detection Consortium (PRECEDE) Collaborate to Improve Surveillance of Early Pancreatic Cancer
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Exosomes functionally deliver siRNAs in vivo to repress tumor growth
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VivaZome enhances Board and Executive Team
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Creative Biolabs: An Expert Active in Exosome Research