Extracellular vesicles (EVs) are nanoparticles found in all biological fluids, capable of transporting biological material around the body. Extensive...
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NeuroSense Therapeutics Reports Positive Results from Stage III ALS Biomarker Study
Preliminary results show levels of disease-related biomarkers remain unchanged in people living with ALS who are treated with standard of care...
Read More »Extracellular vesicles and cancer therapy
Oxidative stress plays a significant role in cancer development and cancer therapy, and is a major contributor to normal tissue injury. The unique characteristics of extracellular vesicles (EVs) have...
Read More »Designer exosomes for targeted delivery of a novel therapeutic cargo
Sorafenib is one of the few effective first-line drugs approved for the treatment of advanced hepatocellular carcinoma (HCC). However, the development of drug resistance is common among individuals with HCC. Recent evidence indicated that...
Read More »Fast and specific enrichment and quantification of cancer-related exosomes by DNA-nanoweight-assisted centrifugation
Exosomes are nanoscale membrane vesicles actively released by cells and play an important role in the diagnosis of cancer-related diseases. However, it is challenging to efficiently enrich exosomes from...
Read More »SARS-CoV-2 and mitochondrial proteins in neural-derived exosomes of COVID-19
As SARS-CoV-2 is known to invade neural cell mitochondria, researchers at UCSF investigated neuropathogenic mechanisms of long-COVID-19...
Read More »An in situ strategy for labelling exosome proteins using engineered ascorbate peroxidase APEX
The extracellular vesicle exosome mediates intercellular communication by transporting macromolecules such as proteins and ribonucleic acids (RNAs). Determining cargo contents with high...
Read More »A tri-channel electrochemical immunobiosensor for combined detections of multiple exosome biomarkers of lung cancer
Current methods for the early diagnosis of cancer can be invasive and costly. In recent years, exosomes have been recognized as potential biomarkers for cancer diagnostics. The common methods...
Read More »Urinary extracellular vesicles and micro-RNA as markers of acute kidney injury after cardiac surgery
University of Leicester researchers hypothesised that measuring changes in urinary levels of EV and miR will predict the onset of acute kidney injury in...
Read More »Heparin affinity chromatography for extracellular vesicle purification and fractionation
The purification of extracellular vesicles (EVs) remains a major hurdle in the progression of fundamental research and the commercial...
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