Can algae enhance skin regeneration and wound healing?

A product of a freshwater single-celled green algae called Euglena gracilis may enhance skin regeneration to speed up wound healing, according to new research published in Advanced Materials Interfaces.

Investigators at Sungkyunkwan University have developed a system based on microvesicles that bud from the cell surface of Euglena gracilis and contain β-glucan, a carbohydrate with immunoregulatory activity, regeneration ability, and antioxidant properties.

Schematic illustration for fabrication of EMVEG using a EG extrusion method.

In laboratory experiments, these microvesicles promoted the proliferation and migration of skin cells, increasing both collagen synthesis and the expression of proliferation-associated proteins. A wound healing test also generated promising results.

“This technique is expected to be applied to other cells, thereby enabling the design of new types of extracellular vesicles that are applicable for skin treatments and care in the pharmaceutical and cosmetic industries,” the authors wrote.

SourceSungkyunkwan University

Ko Y, Baek H, Hwang JH, Kim Y, Lim KM, Kim J, Kim JW. (2023) Nonanimal Euglena gracilis-Derived Extracellular Vesicles Enhance Skin-Regenerative Wound Healing. Adv Mat Inter [Epub ahead of print]. [article]

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