Researchers used neural stem cell-derived extracellular vesicles to improve antisense oligonucleotide delivery to the nervous system, delaying ALS progression and preserving motor...
Read More »UD-developed method helps researchers study proteins involved in plant health, disease
Researchers developed an improved plant proteomics method, revealing how extracellular vesicles carry immune-related proteins and contribute to plant defense responses against fungal infections...
Read More »Study identifies protein signature that could help detect advanced fibrosis in liver disease
Researchers identified an 11-protein signature in circulating extracellular vesicles associated with advanced liver fibrosis, offering potential biomarkers
Read More »Electronic sensor detects early Parkinson’s markers in blood
Researchers developed an electronic sensor that analyzes neuronal extracellular vesicles in blood, detecting Parkinson's disease-associated proteins with 90.9% accuracy in an initial clinical evaluation...
Read More »Pyr-PICsomes – novel programmable nanovesicles for hydrostatic pressure sensing
Researchers developed extracellular vesicles-inspired fluorescent nanovesicles that detect hydrostatic pressure, offering new opportunities to measure pressure changes in biological tissues and complex aqueous environments...
Read More »Developing Novel Cancer Therapy That Disrupts Communication Between Cancer Cells and Cancer-associated fibroblasts
Extracellular vesicles help cancer cells communicate with surrounding stromal cells, and targeted protein degradation may disrupt this signaling network to suppress tumor growth...
Read More »Engineering extracellular vesicles for targeted surface display
Engineered extracellular vesicles displaying functional nanobodies through optimized CD9 sites may provide a flexible platform for targeted delivery, diagnostics and multifunctional therapeutic designs...
Read More »Researchers find way to treat lung cancer and associated muscle wasting at the same time
Unlike extracellular vesicles, lipid nanoparticles delivered follistatin mRNA to lung tumors, reducing tumor burden while also promoting muscle...
Read More »Engineered extracellular vesicles can learn from decades of liposome research
Engineered extracellular vesicles offer promising drug delivery capabilities, but decades of liposome research provide important lessons for overcoming...
Read More »Exercise-enriched extracellular vesicles may help maintain aging cartilage
Exercise alters extracellular vesicles by enriching microRNA-29, which may support healthier aging cartilage through regulation of the longevity...
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