Technology

Blood vessels deliver oxygen and nutrients that sustain tumor growth and enable the dissemination of cancer cells to distant sites and the recruitment of intratumoral immune cells. In addition, the structural and functional abnormalities of the tumor vasculature foster the ...

Extracellular vesicles (EVs) have the potential to be utilized as disease-specific biomarkers. Although strategies for on-chip isolation and detection of EVs have recently been developed, they need preprocessing of clinical samples and are not accurate enough for...

It has been a long-held consensus that immune reactions primarily mediate the pathology of chronic obstructive pulmonary disease (COPD), and that exosomes may participate in immune regulation in COPD...

Small extracellular vesicles (sEVs) produced by antigen-presenting cells represent a novel mechanism of cell-to-cell communication. The sEVs have been shown to drive Th1-type adaptive immune responses against intracellular infections such as Salmonella. Researchers from the University of Florida have demonstrated ...

Exosomes are tiny vesicles secreted by cells that contain short pieces of RNA called microRNA (miRNA). These miRNAs can regulate cell processes..

Detection of the cancer microenvironment may soon become much easier with the help of a new molecular biosensor recently developed by a team...

A new mechanism that slows down and may even prevent the natural ageing of immune cells – one of the nine ‘hallmarks of ageing’* – has been identified by an international team led by UCL scientists...

Repairing critical bone defects is a complex problem in the clinic. The periosteum rich in nerve plays a vital role in initiating and regulating bone regeneration. However, current studies have paid little...

Targeting cancer cell exosome release and biogenesis represents a potentially efficient means to treat tumors and prevent cancer recurrence /metastasis; however, the complexity and time-consuming nature of currently employed methods...

Understanding the genetic drivers of cancer can inform treatment decisions and provide additional options for patients if targeted therapies are...