Technology

New research shows that mesenchymal stromal cells exosomes (MEx) can prevent preeclampsia in pre-clinical mouse models, likely through changing the intrauterine environment. This image shows uptake of MEx (red) into mouse uterine cells (blue). (Image: Elizabeth Taglauer, Boston Children’s Hospital) ...

As the fields of aging and neurological disease expand to liquid biopsies, there is a need to identify informative biomarkers for the diagnosis of neurodegeneration and other age-related disorders such as cancers. A means of high-throughput screening of biomolecules relevant ...

Breast cancer is a leading cause of cancer mortality in women. Despite advance in its management, the identification of new options for early stage...

Capricor Therapeutics, a clinical-stage biotechnology company focused on the discovery, development and commercialization of first-in-class cell- and exosome-based therapeutics for the treatment and...

Exosomes mediate intercellular communication in health and disease. Conventional assays are limited in profiling exosomes secreted from large populations of cells and are unsuitable for studying the functional consequences of individual cells exhibiting varying...

Liquid biopsy-based biomarkers, including microRNAs packaged within extracellular vesicles, are promising tools for patient management. The cytokine tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is related to PCa progression and is found in the semen of patients with PCa. ...

Melanoma cells release extracellular vesicles (EVs) subpopulations which differ in size, phenotype and molecular content. Melanoma derived EVs play a role...

Exosomes, recently re‐named “small extracellular vesicles” or “sEV,” are emerging as an intercellular communication system. Quantification of the molecular cargo exosomes carry by on‐bead flow...

Exosomes, the endosome-derived bilayered extracellular nanovesicles with their contribution in many aspects of cancer biology, have become one...

Liquid droplets have been studied for decades and have recently experienced renewed attention as a simplified model for numerous fascinating physical...