Methods

Extracellular vesicles (EVs) transfer bioactive molecules between cells in a process reminiscent of enveloped viruses. EV cargo delivery is thought to...

Extracellular vesicles, especially small extracellular vesicles (sEVs) are now accepted as important messengers in cell-to-cell communication and as a promising drug delivery platform. They are involved..

Exosomes, as a potential biomarker in liquid biopsy, hold great potential for early cancer diagnosis and monitoring of highly metastatic cancer cells. Recently, a group of researchers proposed a novel electrochemical biosensor for sensitive identification and detection of target exosomes. ...

Exosomes are lipid-bilayer nanoscale membrane particles (typically <200 nm in size) secreted by numerous cell types. Since exosomes exhibit a naturally derived composition and function as intercellular communication tools through the transfer and delivery of biomolecules, they have demonstrated great ...

Extracellular vesicles (EVs) are nanosized circulating assemblies that contain biomarkers considered promising for early diagnosis within neurology, cardiology, and oncology. Recently, acoustic wave...

Cancer-derived small extracellular vesicles (csEVs) play critical roles in the genesis and development of various cancers. However, accurate detection of low-abundance csEVs remains particularly challenging...

New methods and tools for isolation and detection of exosomes are constantly being developed, but it can be difficult to know which to use. Biotium scientists provide detailed protocols for isolating exosomes...

In this study, researchers from Uppsala University, demonstrate the fabrication, characterization, and application of a microchip-based electrokinetic biosensor which exploits streaming current for signal transduction. The sensor chips, fabricated using standard silicon fabrication techniques, are based on Si-glass microfluidics offering ...

Liquid biopsy for determining the presence of cancer and the underlying tissue of origin is crucial to overcome the limitations of existing tissue biopsy and imaging-based techniques by capturing critical...

Extracellular vesicles (EVs) are nanoscale vesicles secreted into the extracellular space by all cell types, including neurons and astrocytes in the brain. EVs play pivotal roles in physiological and pathophysiological