Extracellular vesicles (EVs) are released by all cells into biofluids such as plasma. The separation of EVs from highly abundant free proteins and similarly...
Read More »DNA-driven photothermal amplification transducer for highly sensitive visual determination of extracellular vesicles
Extracellular vesicles (EVs) are crucial focus of current biomedical research and future medical diagnosis. However, the requirement for specialized sophisticated instruments for quantitative readouts...
Read More »New production process for therapeutic nanovesicles
Researchers at the University of Basel have developed an efficient method for the preparation of therapeutic nanovesicles, thereby fulfilling a key prerequisite for industrial production. The method...
Read More »Isolation of bovine milk exosome using electrophoretic oscillation assisted tangential flow filtration
Tangent flow-driven ultrafiltration (TF-UF) is an efficient isolation process of milk exosomes without morphological deformation. However, the TF-UF approach with micro-ultrafiltration SiNx membrane filters suffers from the clogging and fouling of micro-ultrafiltration membrane filter pores with large bioparticles. Thus, it is ...
Read More »On-chip immunocapture of serum neuronal exosomes for Parkinson’s Disease diagnostics
The analysis of cargo proteins in exosome subpopulations has considerable value in diagnostics but a translatable impact has been limited by...
Read More »Multi-parametric orthogonal characterization of extracellular vesicles by liquid chromatography combined with in-line light scattering and fluorescence detection
Extracellular vesicles (EVs) are membrane enclosed biological nanoparticles with potential as diagnostic markers and carriers for therapeutics. Characterization of EVs poses severe challenges due to their...
Read More »Machine learning-based label-free SERS profiling of exosomes for accurate fuzzy diagnosis of cancer
Exosomes are a class of extracellular vesicles secreted by cells, which can be used as promising noninvasive biomarkers for the early diagnosis and...
Read More »A standardized method for plasma extracellular vesicle isolation and size distribution analysis
Researchers at the University of North Carolina School of Medicine have developed a workflow for isolation and quantification of plasma extracellular...
Read More »A dual aptamer recognition-based fluorescent biosensor for extracellular vesicles assays with high sensitivity and specificity
Cancer-derived extracellular vesicles (EVs) play a crucial role in intercellular information transmission, tumor metastasis and invasion, which has become one of the most promising biomarkers for tumor liquid...
Read More »EXTRA-CRISPR assay to quantify miRNA biomarkers in extracellular vesicles for liquid-biopsy-based cancer diagnosis
A team of University of Florida researchers has developed a promising new CRISPR-powered method for noninvasive blood tests that could help clinicians diagnose cancer at earlier stages...
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