Exosomes are nanoscale membrane vesicles actively released by cells and play an important role in the diagnosis of cancer-related diseases. However, it is challenging to efficiently enrich exosomes from...
Read More »An in situ strategy for labelling exosome proteins using engineered ascorbate peroxidase APEX
The extracellular vesicle exosome mediates intercellular communication by transporting macromolecules such as proteins and ribonucleic acids (RNAs). Determining cargo contents with high...
Read More »A tri-channel electrochemical immunobiosensor for combined detections of multiple exosome biomarkers of lung cancer
Current methods for the early diagnosis of cancer can be invasive and costly. In recent years, exosomes have been recognized as potential biomarkers for cancer diagnostics. The common methods...
Read More »Heparin affinity chromatography for extracellular vesicle purification and fractionation
The purification of extracellular vesicles (EVs) remains a major hurdle in the progression of fundamental research and the commercial...
Read More »Size separation of exosomes and microvesicles using flow field-flow fractionation/multiangle light scattering
Extracellular vesicles (EVs) are cell-derived membrane-bound particles, including exosomes and microvesicles that differ in cellular origin, content, and lipid composition. This study reports that exosomes..
Read More »Si nanowire Bio-FET for electrical and label-free detection of cancer cell-derived exosomes
Exosomes are highly important in clinical diagnosis due to their high homology with their parental cells. However, conventional exosome detection methods..
Read More »A more efficient method to load isolated biovesicles with cargo that can functionally modified recipient cells
Cell membrane-based biovesicles (BVs) are important candidate drug delivery vehicles and comprise extracellular vesicles, virus-like particles, and lentiviral vectors. Here, Harvard Medical School researchers introduce a non-enzymatic assembly of purified BVs, supercharged proteins, and plasmid...
Read More »An optimized method for the isolation of urinary extracellular vesicles for detection of biomarkers for radiation exposure
Urinary extracellular vesicles (EVs) are a source of biomarkers with broad potential applications across clinical research, including monitoring radiation exposure. A key limitation to their implementation is...
Read More »Damage-free and time-saving platform for continuous sorting and detection of exosomes and host cells in human serum
The growth relationship between exosomes (EXOs) and the host cells is highly desired for tumor evaluations, which puts forward high demand on the accurate and convenient acquisition of their...
Read More »Extracellular Vesicle (EV) Dot Blotting for Multiplexed EV Protein Detection in Complex Biofluids
Extracellular vesicles (EVs) are nanoscale vesicles secreted from cells, carrying biomolecular cargos similar to their cells of origin. Measuring the protein..
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