Methods

Extracellular vesicles (EVs) are released by all cells into biofluids such as plasma. The separation of EVs from highly abundant free proteins and similarly...

Extracellular vesicles (EVs) are crucial focus of current biomedical research and future medical diagnosis. However, the requirement for specialized sophisticated instruments for quantitative readouts...

Researchers at the University of Basel have developed an efficient method for the preparation of therapeutic nanovesicles, thereby fulfilling a key prerequisite for industrial production. The method...

Tangent flow-driven ultrafiltration (TF-UF) is an efficient isolation process of milk exosomes without morphological deformation. However, the TF-UF approach with micro-ultrafiltration SiNx membrane filters suffers from the clogging and fouling of micro-ultrafiltration membrane filter pores with large bioparticles. Thus, it is ...

The analysis of cargo proteins in exosome subpopulations has considerable value in diagnostics but a translatable impact has been limited by...

Extracellular vesicles (EVs) are membrane enclosed biological nanoparticles with potential as diagnostic markers and carriers for therapeutics. Characterization of EVs poses severe challenges due to their...

Exosomes are a class of extracellular vesicles secreted by cells, which can be used as promising noninvasive biomarkers for the early diagnosis and...

Researchers at the University of North Carolina School of Medicine have developed a workflow for isolation and quantification of plasma extracellular...

Cancer-derived extracellular vesicles (EVs) play a crucial role in intercellular information transmission, tumor metastasis and invasion, which has become one of the most promising biomarkers for tumor liquid...

A team of University of Florida researchers has developed a promising new CRISPR-powered method for noninvasive blood tests that could help clinicians diagnose cancer at earlier stages...