Methods

Aptasensor Detection of Cancerous Exosomes

exosomes

Exosomes are extracellular vesicles (50-100 nm) circulating in biofluids as intercellular signal transmitters. Although the potential of cancerous exosomes as tumor biomarkers is promising, sensitive and rapid detection of exosomes remains challenging. Researchers from the University of Florida combined the ...

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Exosome separation using microfluidic systems

exosomes

Exosomes, nanovesicles secreted by most types of cells, exist in virtually all bodily fluids. Their rich nucleic acid and protein content make them potentially valuable biomarkers for noninvasive molecular diagnostics. They also show promise, after further development, to serve as ...

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Charge-based precipitation of extracellular vesicles

exosomes

Vesicular-mediated communication between cells appears critical in many biological processes. Extracellular vesicles (EVs) released from healthy and diseased cells are involved in a network of exchange of biologically active molecules. Since EVs present in biological fluids carry the signature of ...

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Characterization of extracellular vesicles by IR spectroscopy

Researchers from the Hungarian Academy of Sciences isolated extracellular vesicles by differential centrifugation from Jurkat T-cell line and investigated by attenuated total reflection Fourier-transform infrared spectroscopy (ATR-FTIR). Amide and CH stretching band intensity ratios calculated from IR bands, characteristic of ...

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