Publications

Central nervous system (CNS) injuries, including stroke, traumatic brain injury, and spinal cord injury, are essential causes of death and long-term disability and are difficult to cure, mainly due to the limited neuron regeneration and the glial scar formation. Researchers ...

Extracellular vesicles (EVs) are released by all cells into biofluids such as plasma. The separation of EVs from highly abundant free proteins and similarly...

In Head and neck cancer (HNC) angiogenesis is essential for tumor progression and metastasis. Small extracellular vesicles (sEVs) from HNC cell lines alter endothelial cell (EC) functions towards a...

Cancers often release molecules into the bloodstream that pathologically alter the liver, shifting it to an inflammatory state, causing fat buildup and impairing its normal detoxifying...

Extracellular vesicles (EVs) are crucial focus of current biomedical research and future medical diagnosis. However, the requirement for specialized sophisticated instruments for quantitative readouts...

Researchers at the University of Basel have developed an efficient method for the preparation of therapeutic nanovesicles, thereby fulfilling a key prerequisite for industrial production. The method...

Autologous conditioned serum (ACS) — a biologic therapy that famous athletes swear by to treat arthritis and sports injuries — also shows benefit for the kind of neurological pain caused by chemotherapy or diabetes. In a study using rodents, Duke ...

Nucleus pulposus stem cells (NPSCs) senescence plays a critical role in the progression of intervertebral disc degeneration (IDD). Stem cell-derived extracellular vesicles (EV) alleviate cellular senescence. Whereas, the underlying mechanism remains unclear. Low stability largely limited the administration of EV ...

Extracellular vesicles (EVs) carry RNA cargo that is believed to be associated with the cell-of-origin and thus have the potential to serve as a minimally...

Scientists are calling for tighter regulation of stem cell treatments, after finding hundreds of clinics worldwide offering unproven ‘therapies’ for conditions as varied as hair loss and Parkinson’s...