Breast cancer is a leading cause of cancer mortality in women. Despite advance in its management, the identification of new options for early stage diagnosis and therapy of this tumor still represents a crucial challenge. Increasing evidence indicates that extracellular ...
Read More »Capricor Therapeutics Announces Publication Demonstrating Methods for Enhanced Potency of Cardiosphere-Derived Exosomes
Capricor Therapeutics, a clinical-stage biotechnology company focused on the discovery, development and commercialization of first-in-class cell- and exosome-based therapeutics for the treatment and prevention of a variety of diseases and disorders, announced today the publication, in collaboration with researchers at ...
Read More »Functional single-cell profiling identifies that exosomes are associated with increased immune cell infiltration in non-metastatic breast cancer
Exosomes mediate intercellular communication in health and disease. Conventional assays are limited in profiling exosomes secreted from large populations of cells and are unsuitable for studying the functional consequences of individual cells exhibiting varying...
Read More »Liquid biopsy-based exo-oncomiRNAs can predict prostate cancer aggressiveness
Liquid biopsy-based biomarkers, including microRNAs packaged within extracellular vesicles, are promising tools for patient management. The cytokine tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is related to PCa progression and is found in the semen of patients with PCa. ...
Read More »FT-IR spectroscopy to show alterations in molecular composition of EV subpopulations from melanoma cell lines in different malignancy
Melanoma cells release extracellular vesicles (EVs) subpopulations which differ in size, phenotype and molecular content. Melanoma derived EVs play a role...
Read More »Evaluation of exosome proteins by on-bead flow cytometry
Exosomes, recently re‐named “small extracellular vesicles” or “sEV,” are emerging as an intercellular communication system. Quantification of the molecular cargo exosomes carry by on‐bead flow...
Read More »Acoustofluidic centrifuge for nanoparticle enrichment and separation
Liquid droplets have been studied for decades and have recently experienced renewed attention as a simplified model for numerous fascinating physical...
Read More »High-sensitivity nanophotonic sensors with passive trapping of analyte molecules in hot-spots
Optical sensors can quantitatively analyze chemical and biological samples by measuring and processing the optical signals produced by the samples. Optical sensors based on infrared absorption spectroscopy can achieve high sensitivity and selectivity in real time...
Read More »Immune response and biomarker transport roles of extracellular vesicles in marine mollusk species
Understanding the immune systems of oysters and clams is important in monitoring the effects of pollution and climate change on the health of molluscan species and the potential impacts on the aquaculture industry. Their immune responses also...
Read More »A new stem cell therapy for regenerating cardiac function in pediatric patients
Dilated cardiomyopathy (DCM) is a condition caused by the weakening of the heart muscle, affecting the ventricles (chambers in the heart that push blood...
Read More »