Central nervous system (CNS) injuries, including stroke, traumatic brain injury, and spinal cord injury, are essential causes of death and long-term disability and are difficult to cure, mainly due to the limited neuron regeneration and the glial scar formation. Researchers ...
Read More »Improved isolation of extracellular vesicles by removal of both free proteins and lipoproteins
Extracellular vesicles (EVs) are released by all cells into biofluids such as plasma. The separation of EVs from highly abundant free proteins and similarly...
Read More »Plasma-derived small extracellular vesicles unleash the angiogenic potential in head and neck cancer patients
In Head and neck cancer (HNC) angiogenesis is essential for tumor progression and metastasis. Small extracellular vesicles (sEVs) from HNC cell lines alter endothelial cell (EC) functions towards a...
Read More »Cancers in distant organs alter liver function
Cancers often release molecules into the bloodstream that pathologically alter the liver, shifting it to an inflammatory state, causing fat buildup and impairing its normal detoxifying...
Read More »DNA-driven photothermal amplification transducer for highly sensitive visual determination of extracellular vesicles
Extracellular vesicles (EVs) are crucial focus of current biomedical research and future medical diagnosis. However, the requirement for specialized sophisticated instruments for quantitative readouts...
Read More »New production process for therapeutic nanovesicles
Researchers at the University of Basel have developed an efficient method for the preparation of therapeutic nanovesicles, thereby fulfilling a key prerequisite for industrial production. The method...
Read More »Exosome component of biologic therapy used by athletes could also ease nerve pain from chemo, diabetes
Autologous conditioned serum (ACS) — a biologic therapy that famous athletes swear by to treat arthritis and sports injuries — also shows benefit for the kind of neurological pain caused by chemotherapy or diabetes. In a study using rodents, Duke ...
Read More »Extracellular vesicle-conjugated functional matrix hydrogels for disc regeneration
Nucleus pulposus stem cells (NPSCs) senescence plays a critical role in the progression of intervertebral disc degeneration (IDD). Stem cell-derived extracellular vesicles (EV) alleviate cellular senescence. Whereas, the underlying mechanism remains unclear. Low stability largely limited the administration of EV ...
Read More »Assessing breast cancer molecular subtypes using extracellular vesicles’ mRNA
Extracellular vesicles (EVs) carry RNA cargo that is believed to be associated with the cell-of-origin and thus have the potential to serve as a minimally...
Read More »Stem cell scientists call for regulation of ‘treatment’ fads
Scientists are calling for tighter regulation of stem cell treatments, after finding hundreds of clinics worldwide offering unproven ‘therapies’ for conditions as varied as hair loss and Parkinson’s...
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