Most cancer diagnostic techniques rely on uncomfortable and invasive procedures, such as biopsies, endoscopies or mammograms. Blood samples could be a less unpleasant option, though...
Read More »ExoSponge – rapid, cost-effective, porous polydimethylsiloxane (PDMS) based cancer-associated extracellular vesicle isolation
Polydimethylsiloxane (PDMS) is an inexpensive robust polymer that is commonly used as the fundamental fabrication material for soft-lithography-based microfluidic devices. Owing to its versatile...
Read More »Isolation and characterisation of exosomes from Chinese hamster ovary (CHO) cells
Exosomes have previously been isolated from Chinese hamster ovary (CHO) cells and their anti-apoptotic properties reported. However, to further...
Read More »Cellular messengers improve cancer therapy
Nano-sized membrane bubbles known as extracellular vesicles activate the immune system in mice and seem to render their tumours sensitive to a type of immunotherapy drug called a checkpoint...
Read More »Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling
Aberrant Wnt activation has been reported in failing cardiomyocytes. Researchers at University Medical Center Göttingen present single cell transcriptome profiling of hearts with inducible cardiomyocyte-specific Wnt activation (β-catΔex3) as well as with...
Read More »Triple study exploits cellular messengers for diagnostics and drug delivery
In a series of three papers on extracellular vesicles (EVs) — particles that cells use to communicate — Skoltech researchers and their colleagues have...
Read More »Nanoscopic tool assesses alternative COVID-19 prevention
Researchers at Kanazawa University report in Nano Letters how high-speed atomic force microscopy can be used to assess the effectivity of spike-neutralizing antibodies for preventing COVID-19. The use of...
Read More »An epithelial-to-mesenchymal transition induced extracellular vesicle prognostic signature in non-small cell lung cancer
Despite significant therapeutic advances, lung cancer remains the leading cause of cancer-related death worldwide. Non-small cell lung cancer (NSCLC) patients have a very poor overall five-year survival rate of...
Read More »Nanovesicles from cells for biomedical applications
NUS scientists have fabricated nano-sized vesicles from cells via a cell shearing approach that can be used for various biomedical applications. Extracellular vesicles (EVs) are naturally occurring...
Read More »E coli-derived outer membrane vesicles relay inflammatory responses to macrophage-derived exosomes
Extracellular vesicles are considered to be an inflammatory factor in several acute and chronic inflammatory diseases. Researchers from Kyoto Prefectural University demonstrate that exosomes from...
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