Researchers used high-speed atomic force microscopy to measure antibody binding to PD-L1 on individual extracellular vesicles, revealing differences in protein accessibility that conventional measurements may miss...
Read More »UD-developed method helps researchers study proteins involved in plant health, disease
Researchers developed an improved plant proteomics method, revealing how extracellular vesicles carry immune-related proteins and contribute to plant defense responses against fungal infections...
Read More »Developing Novel Cancer Therapy That Disrupts Communication Between Cancer Cells and Cancer-associated fibroblasts
Extracellular vesicles help cancer cells communicate with surrounding stromal cells, and targeted protein degradation may disrupt this signaling network to suppress tumor growth...
Read More »Exercise-enriched extracellular vesicles may help maintain aging cartilage
Exercise alters extracellular vesicles by enriching microRNA-29, which may support healthier aging cartilage through regulation of the longevity...
Read More »An anti-fibrotic drug could be repurposed to control cell communication
SD-208 reduced extracellular vesicles release by redirecting CD63-positive vesicle compartments toward lysosomes, revealing a potential new way...
Read More »Electronic profiling of neuronal extracellular vesicles enables early prediction of Parkinson’s disease
Neuronal extracellular vesicles carrying distinct alpha-synuclein forms may provide a blood-based source of biomarkers for earlier and less invasive...
Read More »A Tiny Worm Helps Scientists Unravel a Genetic Clue to Kidney Disease
Extracellular vesicles and ciliary signaling in C. elegans help reveal how an ADPKD-associated mutation disrupts polycystin protein localization...
Read More »Found in the Dark: How AI Helped Reveal a Hidden Cellular Communication Network
TM184C regulates intercellular vesicle exchange and autophagy, offering insights relevant to extracellular vesicles, cell communication, and mechanisms that may contribute to disease...
Read More »Fungal infections: A surprising downside of the immune response
Neutrophil-derived extracellular vesicles can coat Candida albicans and reduce fungal uptake by immune cells, revealing an unexpected role for EVs in host-pathogen interactions...
Read More »Extracellular vesicles help shape neural development in EPM1 epilepsy
Extracellular vesicles carrying Sonic Hedgehog help guide neural development, while disrupted EV signaling in EPM1 may alter neuronal identity and...
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