Chronic wounds remain an unresolved medical issue due to major social and therapeutic repercussions that require extensive focus. Recent related...
Read More »Migrasomes, a new mode of intercellular communication
Migrasomes are newly discovered extracellular vesicles (EVs) that are formed in migrating cells and mediate intercellular communication. However, their size, biological generation, cargo packaging...
Read More »Bioengineered exosomal-membrane-camouflaged abiotic nanocarriers
A bio-inspired strategy has recently been developed for camouflaging nanocarriers with biomembranes, such as natural cell membranes or subcellular structure-derived membranes. This strategy endows cloaked nanomaterials with improved interfacial...
Read More »Therapeutic values of exosomes in cosmetics, skin care, tissue regeneration, and dermatological diseases
Exosomes are small extracellular nanovesicles that are released by cells, and their potential has been explored for use in cosmetics, skin care, tissue regeneration, and dermatological diseases. The therapeutic..
Read More »Exosomal miRNAs in the tumor microenvironment
Multiple myeloma (MM) is a malignancy of plasma cells in the bone marrow and is characterized by the clonal proliferation of B-cells producing defective monoclonal immunoglobulins. Despite the latest...
Read More »The role of extracellular vesicles in cancer
Intercellular communication is a key feature of cancer progression and metastasis. Extracellular vesicles (EVs) are generated by all cells, including cancer cells, and recent studies have identified EVs...
Read More »The potential use of mitochondrial extracellular vesicles as biomarkers or therapeutical tools
The mitochondria play a crucial role in cellular metabolism, reactive oxygen species (ROS) production, and apoptosis. Aberrant mitochondria...
Read More »Urinary extracellular vesicles carry valuable hints through mRNA for the understanding of endocrine hypertension
Urinary extracellular vesicles (uEVs), released from cells of the urogenital tract organs, carry precious information about originating tissues. The study of molecules transported through uEVs such as proteins...
Read More »Exosome-based liquid biopsy approaches in bone and soft tissue sarcomas
The knowledge of exosome impact on sarcoma development and progression has been implemented in preclinical studies thanks to technological...
Read More »Bioengineered MSC-derived exosomes in skin wound repair and regeneration
Refractory skin defects such as pressure ulcers, diabetic ulcers, and vascular ulcers represent a challenge for clinicians and researchers in many aspects. The treatment strategies for wound healing have high cost and limited efficacy. To ease the financial and psychological ...
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