Exosomes are membrane‐bound nanovesicles containing complex cargoes including proteins, lipids, and nucleic acids (mRNAs and microRNAs), which can be derived from most cells. Increasing evidence has implicated exosomes as key players in...
Read More »The microfluidic toolbox for analyzing exosome biomarkers
As the fields of aging and neurological disease expand to liquid biopsies, there is a need to identify informative biomarkers for the diagnosis of neurodegeneration and other age-related...
Read More »Trends in Research on Exosomes in Cancer Progression and Anticancer Therapy
Exosomes, the endosome-derived bilayered extracellular nanovesicles with their contribution in many aspects of cancer biology, have become one...
Read More »Circulating exosomes in cardiovascular disease
Exosomes are a group of nanosized extracellular vesicles that include various bioactive nucleic acids, lipids, and proteins. They originate from membrane invagination and are released by exocytosis, which...
Read More »Insights Into the Proteomic Profiling of Extracellular Vesicles for the Identification of Early Biomarkers of Neurodegeneration
Extracellular vesicles (EVs) are involved in the development and progression of neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease. Moreover, EVs have the capacity to modify the...
Read More »Exosomes in Parkinson Disease
Parkinson disease (PD) is a prevalent neurodegenerative disease, in which the formation of misfolded and aggregated α‐synuclein is a key neuropathological hallmark. Recent studies reveal that extracellular vesicles such as exosomes present a potential mechanism for propagation of pathological α‐synuclein ...
Read More »Extracellular vesicles in blood: are they viable as diagnostic and predictive tools in breast cancer?
Extracellular vesicles (EVs), often described as mini-maps of their cells of origin, are found in the bloodstream and can be rich sources of cargo...
Read More »Biological properties and therapeutic effects of plant-derived nanovesicles
Exosomes-like nanoparticles can be released by a variety of plants and vegetables. The relevance of plant-derived nanovesicles (PDNVs) in interspecies communication is derived from their content in biomolecules (lipids, proteins, and miRNAs), absence of...
Read More »Exosomes – Cell-Derived Nanoplatforms for the Delivery of Cancer Therapeutics
Exosomes are cell-secreted nanovesicles that naturally contain biomolecular cargoes such as lipids, proteins, and nucleic acids. Exosomes mediate intercellular communication, enabling the transfer biological signals from the donor cells to the recipient cells. Recently, exosomes are emerging as promising drug ...
Read More »Exosomes as therapeutic solutions for pancreatic cancer
Pancreatic cancer (PC) is one the deadliest cancers worldwide. It is characterized by elevated mortality rates because of the lack of effective diagnostic methods, the dense stroma that shields the tumor from effective drug penetration, and the emergence of chemoresistance. ...
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