Discovering the secrets of diseases from tear extracellular vesicles (EVs) is well-recognized and appreciated. However, a precise understanding of the interaction network between EV populations and their biogenesis from our body requires more in...
Read More »Inhibition of glioma cells’ proliferation by doxorubicin-loaded exosomes via microfluidics
Malignant glioma is a fatal brain cancer. Accumulated evidence has demonstrated that exosomes can cross the blood-brain barrier (BBB), suggesting their potential use as drug delivery vehicles to glioma. Therefore, various loading methods of anticancer agents into exosomes have been ...
Read More »Extracellular vesicles revive cells after a heart attack
Extracellular vesicles (EVs) — nanometer sized messengers that travel between cells to deliver cues and cargo — are promising tools for the next generation of therapies for everything from autoimmune and neurodegenerative diseases to cancer and tissue injury. EVs ...
Read More »Exosomes and beyond: translation of small molecules and cellular organelles
Phil Yang of the Stanford Cardiovascular Institute presents webinar entitled Exosomes and beyond: translation of small molecules and cellular organelles
Read More »Novel applications of MSC-derived exosomes for myocardial infarction therapeutics
Cardiovascular diseases (CVDs) are the leading cause of mortality and morbidity globally, representing approximately a third of all deaths...
Read More »Crosstalk among colon cancer-derived exosomes, fibroblast-derived exosomes, and macrophage phenotypes in colon cancer metastasis
Cellular crosstalk is an important mechanism in the pathogenesis of inflammatory disorders and cancers. One significant means by which cells communicate with each other is through the release of exosomes. Exosomes are extracellular vesicles formed by the...
Read More »APS and SPR honor exosome researcher with the 2020 Mary Ellen Avery Award
The American Pediatric Society (APS) and the Society for Pediatric Research (SPR) are pleased to announce Stella Kourembanas, MD, as the recipient of the 2020 Mary Ellen Avery Award, which honors a pediatric investigator who has made...
Read More »Analyzing bacterial extracellular vesicles in human body fluids by orthogonal biophysical separation and biochemical characterization
Gram-negative and Gram-positive bacteria release a variety of membrane vesicles through different formation routes. Knowledge of the structure, molecular cargo and function of bacterial extracellular...
Read More »Couple charged with stealing exosome-related trade secrets from Nationwide Children’s Hospital Research Institute
A former Dublin, Ohio, couple has been charged with crimes related to stealing exosome-related trade secrets concerning the research, identification and treatment of a range of pediatric medical conditions...
Read More »Multiplexed immunophenotyping of circulating exosomes on nano-engineered ExoProfile chip
Circulating exosomes have been studied as a promising biomarker for non-invasive cancer diagnosis, as they are implicated in tumor initiation, progression, and metastasis. However, the clinical significance of circulating exosomes has not been revealed thoroughly, due to the technical limitation ...
Read More »