Exosomes are nanoscale vesicles generated by cells for intercellular communication. Due to their composition, significant research has been conducted to transform these particles into specific delivery systems for various disease states. Researchers from the NIBIB discuss the common isolation and loading methods of exosomes, some of the major roles of exosomes in the tumor microenvironment, as well as discuss recent applications of exosomes as drug delivery vessels and the resulting clinical implications.
Clinical implications of exosomes – targeted drug delivery for cancer treatment
Massey AE, Malik S, Sikander M, Doxtater KA, Tripathi MK, Khan S, Yallapu MM, Jaggi M, Chauhan SC, Hafeez BB. (2021) Clinical Implications of Exosomes: Targeted Drug Delivery for Cancer Treatment. Int J Mol Sci 22(10), 5278. [article]