Creative Biolabs, a prominent biotechnology company, proudly introduces its innovative line of all-encompassing exosome engineering solutions, aimed at propelling scientific advancements and driving therapeutic innovations in the field.
Exosomes, which are tiny extracellular vesicles generated by cells, have grown into effective means of intercellular interactions and hold enormous promise in various applications, both procedures for diagnosis and therapy. Recognizing the tremendous possibilities that exosomes offer, Creative Biolabs provides tailored services to assist researchers and drug developers in realizing the full benefits of exosomes.
“Characterizing exosomes in body fluids is widely recognized as a valuable source of information for early detection, disease monitoring, and the development of effective treatments for cancer and autoimmune diseases,” stated a scientist at Creative Biolabs.
Taking the crucial first step, Creative Biolabs has developed a variety of protocols to better characterize exosomes. The advanced solutions adopted include:
* Nanoparticle tracking analysis (NTA), which directly visualizes light scattered from exosomes or microbubbles in liquid suspensions. Light scattered by the laser beam is then captured by an optical microscope and imaged.
* Analysis of exosomes’ surface proteins using their surface biomarkers, providing key insights into the physiological state of their parental cells. One technique used for this is FACS, which analyzes and classifies individual exosomes based on specific fluorescently labeled antibodies and the light scattering properties of vesicles. Western blotting identifies the presence and expression level of a given protein on the exosome’s surface, based on the size and color intensity of the protein bands on the blotting membrane.
* Mass spectrometry (MS), an analytical technique used to identify proteins carried by exosomes and determine whether a sample contains protein aggregates or other contaminants.
* Tunable resistive pulse sensing, allowing high-throughput single-particle measurements of colloidal and/or biomolecular analytes, providing information about the size of exosomes.
Separating exosomes from a variety of cellular debris and interfering components is a crucial step that must be taken as well. Creative Biolabs provides exosome isolation services covering various cell types and multiple sources of biological fluids, including dendritic cells, tumor cells, plasma, urine, serum, cerebrospinal fluid (CSF), etc.
Furthermore, exosomes possess unique capabilities in carrying and delivering cargo between cells, making them invaluable in various research and application fields. Recognizing this, Creative Biolabs excels in exosome drug loading, a transformative strategy for targeted drug delivery.
Leveraging innovative cargo loading techniques, the company enables efficient loading of various therapeutic cargoes, including small molecules, nucleic acids, peptides, and proteins, into exosomes. This method allows for targeted administration to particular cells or tissues while improving medication stability and lengthening the time it spends in circulation.
“Creative Biolabs remains committed to providing the scientific community with advanced tools and services to unlock the full potential of exosomes. We are excited to support researchers in their quest to translate scientific discoveries into clinical breakthroughs,” proudly stated the scientist.
For more information on exosome-related services supported by Creative Biolabs, please visit
About Creative Biolabs
Creative Biolabs is a leading provider of advanced research and development solutions in the field of exosome-based technologies. With a team of highly experienced scientists, state-of-the-art facilities, and cutting-edge technologies, Creative Biolabs is dedicated to supporting academic and industrial researchers worldwide in harnessing the full potential of exosomes for therapeutic applications.