Scientists have found that proteins, lipids, metabolites, and nucleic acids delivered by exosomes into cells can alter their biological response, which can promote or restrain the specific disease. They have been proved to be related with immune responses, viral pathogenicity, pregnancy, cardiovascular diseases, cancer progression, etc. Recently, more and more researches are trying to explore more about exosomes.
With more than 15 years of experience, Creative Biolabs has gathered a team of exosome experts dedicated to serving comprehensive services and first-class products in the field of exosome research. Now, it introduced one-stop exosome proteomics services and exosome lipidomics & meatbolimics services to facilitate related research.
The proteins in exosomes have long been explored since the initial description. Novel technologies for antibody-based detection, such as western blotting and immuno-EM, lead to the possibility of identifying unknown proteins.
Based on these leading technologies, Creative Biolabs is skillful and experienced on analyzing qualitative and quantitative features of exosomal proteins. The high-throughput proteomic analyses are able to reveal the presence of extracellular matrix and cell surface proteins including collagens, galectin, and integrins. Focusing on exosome proteomics studies all along, Creative Biolabs provides detailed protocols for worldwide customers with quantitative analysis of targeted exosomal proteins.
Exosomes are also enriched with lipids and their accumulation in cells might influence recipient cell homeostasis, making them potential biomarkers for lipid-related diseases. In addition to lipids, exosomes carry a broad range of metabolites that play an active role in the target cell.
Creative Biolabs has rich experience in making use of powerful facilities to analyze the complexity of lipids and metabolites, including liquid chromatography (LC), mass spectrometry (MS) or LC coupled MS equipment. Scientists at Creative Biolabs will complete the report with identifications, mass/charge ratios, and differential analysis as long as the samples or purified exosomes are received.
“We are providing a one-stop design with fast profiling. With Cutting-edge apparatuses, we can provide you with reliable data and reproducible process for any disease-specific biomarker discovery,” introduced by a senior scientist at Creative Biolabs. “Our sophisticated shotgun method and targeted assays for lipidomics and metabolomics research can promote biomarker discovery and drug development to the next level.”
In addition to the aforementioned services, Creative Biolabs also provides well-established platforms for other exosome analysis services including exosome characterization, exosome quantification, and exosome profiling.
More information can be found on https://www.creative-biolabs.com/exosome.