Abstract: More and more scientists are interested in exosomes, since they can participate in the body’s immune response, antigen presentation, cell migration, cell differentiation, and tumor invasion, etc. As an expert in exosome research, Creative Biolabs is committed to offering the first-rate services of exosome targeting.
Exosomes, providing means for intercellular exchange of macromolecules, play an important role in the development of several diseases, specifically in modulating cancer microenvironment and the immune response. Recently, several studies have shown that exosomes express some lipids and cell adhesion molecules and ligands naturally targeting certain types of recipient cells, which suggests that exosomes have natural targeting ability based on donor cells and can act as an efficient tool for targeting delivery.
With years of experiences in exosome technology, Creative Biolabs has combined the delivery capabilities of exosomes with targeting technology and biomolecular engineering approaches, and now offers the custom services of exosome targeting to escalate the development of nanoparticles for drug delivery and vaccine design.
- Exosome Display
Creative Biolabs is skillful in using exosome display technology for various kinds of research purposes and clinical applications. Firstly, exosome display technology can be used to generate antibodies against different targets, such as G protein-coupled receptors (GPCRs). Secondly, ligand fragments or homing peptides addressed on the exosomal surface confer exosome targeting capability, which has been used for the targeted delivery of chemotherapy drugs and RNA therapeutics. Thirdly, exosome display provides a convenient platform, presenting membrane proteins in a native conformation and environment, and recombinant exosomes bearing putative drug targets could also be used to screen cognate ligands or small molecules.
- Targeting Exosome Lentivirus Vector Construction
Research has found that exosome targeting can be achieved by the construction of a lentivirus vector and scientists at Creative Biolabs have developed an exosome targeting peptide for interested proteins fusion, producing lentivectors that are able to deliver the interested proteins into exosomes.
“With the help of a professional expert team and cutting-edge technologies for exosome targeting, we can now provide custom exosome services with the best quality and the most competitive price. Our team has helped clients successfully accelerate their projects and will continue to learn from the experience to provide better services to future partners.” as introduced by Bella Smith, the Business Development Executive at Creative Biolabs.
Further information on exosome-related services and products at Creative Biolabs can be found on https://www.creative-biolabs.com/exosome.
About Creative Biolabs
Empowered by leading technology and years of experience in biomedical science, Creative Biolabs focuses on offering a full range of exosome-related services and products. The comprehensive services covering exosome sampling, analysis, manufacturing, and exosome-based application. The high-quality exosome-related products involving all aspects of exosome research, including exosome purification, exosome qualification, exosome antibody as well as exosome engineering.
Source – Creative Biolabs