Immune-mediated rejection of donor tissues is one of the largest challenges in transplant biology. While routine biopsy to monitor transplanted organs can be informative, this procedure is invasive and carries several risks. In this episode, Prashanth Vallabhajosyula and colleagues evaluated changes in transplant-derived exosomes in murine models and human transplant recipients. Their work indicates that changes in donor-derived exosomes can be used to noninvasively monitor transplant rejection.
Good things come in small packages: roles of exosomes as therapy delivery tools, therapeutic targets and potential biomarkers
March 23, 2021
December 3, 2020
Uncovering the Heterogeneity of Extracellular Vesicles Derived From Amniotic Epithelial Cells Associated With Pregnancy Complications and Culture Conditions
November 10, 2020
October 26, 2020
July 20, 2020