Engineered Extracellular Vesicles as a Reliable Tool in Cancer Nanomedicine

Fast diagnosis and more efficient therapies for cancer surely represent one of the huge tasks for the worldwide researchers’ and clinicians’ community. In the last two decades, our understanding of the biology and molecular pathology of cancer mechanisms, coupled with the continuous development of the material science and technological compounds, have successfully improved nanomedicine applications in oncology. This review argues on nanomedicine application of engineered extracellular vesicles (EVs) in oncology. All the most innovative processes of EVs engineering are discussed together with the related degree of applicability for each one of them in cancer nanomedicines.

Schematic view of the flow of the different steps concerning the direct and indirect engineering of extracellular vesicles (EVs) for cancer diagnosis and therapy applications.