Exosomes a big topic at AACR meeting this week

Presentation Authors Session
Sun, Apr 17, 1:00 – 5:00 PM
423A/30 – A tumor-associated mRNA localizing in circulating exosomes as a novel serological marker for pancreatic cancer: the retrospective clinical study
Keisuke Taniuchi. Kochi University, Nankoku, Japan Poster Session
PO.CL10.11. Biomarkers
Sun, Apr 17, 1:00 – 5:00 PM
Sun, Apr 17, 1:00 – 5:00 PM
LB-064/17 – Proteomic analysis of exosomes purified from HPV+ and HPV- oral squamous cell carcinoma cell lines
Vivian F. Wu, Zhanxiang Wang. EVMS, Norfolk, VA Late-Breaking Poster Session
LBPO.CH01. Late-Breaking Research: Cancer Chemistry
Sun, Apr 17, 1:00 – 5:00 PM
Sun, Apr 17, 5:20 – 5:35 PM
906 – Exosomes from mutant TP53 cancer cells polarize tumor associated macrophages
Tomer Cooks1, Ioannis S. Pateras2, Keval M. Patel3, Tim Forshew4, Vassilis G. Gorgoulis2, Curtis C. Harris1. 1NCI, Bethesda, MD; 2University of Athens, Athens, Greece; 34- Addenbrooke’s Hospital, Cambridge, United Kingdom; 4UCL cancer Institute, London, United Kingdom Minisymposium
MS.TB06.01. Immunomodulation in Cancer
Sun, Apr 17, 4:15 – 6:15 PM
Mon, Apr 18, 8:00 AM – 12:00 PM
1648/5 – Ionizing radiation switches the function of tumor-derived exosomes from messengers of tolerance to inducers of antitumor immunity
Julie M. Diamond1, Jessica R. Chapman1, Beatrix Ueberheide1, Silvia C. Formenti2, Sandra Demaria2. 1NYU School of Medicine, New York, NY; 2Weill Cornell Medicine, New York, NY Poster Session
PO.TB09.01. Radiation Science
Mon, Apr 18, 8:00 AM – 12:00 PM
Mon, Apr 18, 8:00 AM – 12:00 PM
1775/12 – Differential expression of exosomes-associated onco-microRNAs in African Americans with prostate cancer
Ahmed A. Moustafa1, Andrew B. Sholl1, Koji Tsumagari1, Mohamed Hassan2, Emad Kandil1, Asim B. Abdel-Mageed1, Zakaria Y. Abd Elmageed1. 1Tulane University School of Medicine, New Orleans, LA; 2University of Mississippi Medical Center, Jackson, MS Poster Session
PO.EP01.07. Race/Ethnicity and Disparities in Diagnosis, Treatment, and Outcomes
Mon, Apr 18, 8:00 AM – 12:00 PM
Mon, Apr 18, 8:00 AM – 12:00 PM
1567/14 – Prostate cancer-derived exosomes alter the metabolic microenvironment of bone marrow pre-metastatic niche through PKM2 to promote bone metastasis
Jinlu Dai1, Yi Lu2, Jian Zhang2, Evan Keller1. 1University of Michigan, Ann Arbor, MI; 2Guangxi Medical University, Nanning, China Poster Session
PO.TB06.01. Cellular and Molecular Mediators of Metastasis
Mon, Apr 18, 8:00 AM – 12:00 PM
Mon, Apr 18, 8:00 AM – 12:00 PM
1579/26 – Exosomes promote ovarian cancer invasion through CD-44 transfer to mesothelial cells
Koji Nakamura, Kenjiro Sawada, Yasuto Kinose, Akihiko Yoshimura, Erika Nakatsuka, Seiji Mabuchi, Tadashi Kimura. Osaka University, Suita, Osaka, Japan Poster Session
PO.TB06.01. Cellular and Molecular Mediators of Metastasis
Mon, Apr 18, 8:00 AM – 12:00 PM
Mon, Apr 18, 8:00 AM – 12:00 PM
1562/9 – miRNAs in exosomes from prostate cancer cells modify normal fibroblasts and osteoblasts favoring tumor spread and metastasis
Eliana Andahur1, Enrique A. Castellon2, Chistian Ramos1, Juan A. Fulla1, Catherine A. Sanchez1. 1Clinica Las Condes, Santiago, Chile; 2Universidad de Chile, Santiago, Chile Poster Session
PO.TB06.01. Cellular and Molecular Mediators of Metastasis
Mon, Apr 18, 8:00 AM – 12:00 PM
Mon, Apr 18, 1:00 – 5:00 PM
1943/3 – A microRNA signature in urinary exosomes for diagnosis of prostate cancer.
Thorarinn Blondal1, Anne I. Rasmussen1, Anni R. Thomsen1, Michael Borre2, Jacob Fredsøe3, Ditte Andreasen1, Torben Falck Ørntoft3, Karina D. Sørensen3, Peter Mouritzen1. 1Exiqon A/S, Vedbaek, Denmark; 2Department of Urology, Aarhus University Hospital, Aarhus, Denmark; 3Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark Poster Session
PO.MCB10.03. Profiling MicroRNA Expression in Cancer
Mon, Apr 18, 1:00 – 5:00 PM
Mon, Apr 18, 1:00 – 5:00 PM
2360/15 – GP350 containing exosomes as DNA vaccine carriers
Viswa Teja Colluru, Douglas G. McNeel. University of Wisconsin – Madison, Madison, WI Poster Session
PO.IM02.10. Therapeutic Antibodies and Vaccines
Mon, Apr 18, 1:00 – 5:00 PM
Mon, Apr 18, 1:00 – 5:00 PM
LB-169/23 – Ovarian cancer cells selectively release exosomes containing tumor suppressor miRNAs to maintain SRC-mediated oncogenic activities
Mohammed H. Rashed1, Pinar Kanlikilicer1, Cristian Rodriguez Aguayo1, Nashwa N. Kabil1, Martin Pichler1, Recep Bayraktar1, Emine Bayraktar1, Cristina Ivan1, Rahul Mitra1, George A. Calin1, Anil K. Sood1, Mohamed F. Abd-Ellah2, Gouda K. Helal2, Gabriel Lopez Berestein1. 1MD Anderson Cancer Center, Houston, TX; 2Faculty of Pharmacy, Al Azhar University, Cairo, Egypt Late-Breaking Poster Session
LBPO.MCB02. Late-Breaking Research: Molecular and Cellular Biology 2
Mon, Apr 18, 1:00 – 5:00 PM
Mon, Apr 18, 1:00 – 5:00 PM
2167/7 – Efficient and rapid cellular delivery of bioactive proteins using EXPLOR: exosomes engineered for protein loading via optically reversible protein-protein interaction
Nambin Yim, Seung-Wook Ryu, Kyungsun Choi, Kwang Ryeol Lee, Seunghee Lee, Hojun Choi, Jiho Park, Daesoo Kim, Wondo Heo, Chulhee Choi. Korea Advanced Inst. of Science & Tech., Daejeon, Korea, Republic of Poster Session
PO.CH01.02. High Throughput Screening and Natural Products
Mon, Apr 18, 1:00 – 5:00 PM
Mon, Apr 18, 1:00 – 5:00 PM
2452/15 – Exosomes as mediators of paracrine signalling that promote invasive behavior in rhabdomyosarcoma
Sandra E. Ghayad1, Ghina Rammal1, Farah Ghamloush2, Hussein Basma2, Raya Saab2. 1Lebanese University, Beirut, Lebanon; 2American University of Beirut, Beirut, Lebanon Poster Session
PO.TB08.02. Pediatric Cancer Molecular Pathways
Mon, Apr 18, 1:00 – 5:00 PM
Mon, Apr 18, 4:35 – 4:50 PM
2668 – The exosomes derived from BM-hMSCs home to glioma and deliver synthetic microRNA mimics after systemic administration
Shinji Yamashita1, Tal Shahar2, Anwar Hossain3, Brittany Parker Kerrigan3, Joy Gumin3, Shoudong Li3, Feng Gao3, Kouji Yamasaki3, Yuzaburo Shimizu3, Frederick F. Lang3. 1Faculty of Medicine, University of Miyazaki, Miyazaki-city, Japan; 2Tel Aviv Medical Center, Israel; 3University of TX, MD Anderson Cancer Center, TX Minisymposium
MS.MCB10.01. LncRNAs, MicroRNAs, and Non-coding RNAs in Cancer
Mon, Apr 18, 3:00 – 5:00 PM
Tue, Apr 19, 8:00 AM – 12:00 PM
3240/13 – Prostate cancer exosomes and their effects on macrophage engulfment and polarization
Evita G. Weagel, Wei Meng, Richard A. Robison, Kim L. O’Neill. Brigham Young University, Provo, UT Poster Session
PO.IM01.01. Innate Immune System, Myeloid Cells, and Tumorigenesis
Tue, Apr 19, 8:00 AM – 12:00 PM
Tue, Apr 19, 8:00 AM – 12:00 PM
2799/10 – Exosomes from hypoxic pancreatic cancer cells confer resistance to subsequent hypoxia insult
Mary C. Patton, Haseeb Zubair, Girijesh K. Patel, Seema Singh, Ajay P. Singh. Mitchell Cancer Institute, Mobile, AL Poster Session
PO.MCB11.01. Hypoxia and Oxidative Stress
Tue, Apr 19, 8:00 AM – 12:00 PM
Tue, Apr 19, 1:00 – 5:00 PM
4094/21 – Exosomes secreted from the noncancerous microenvironment promote proliferation, migration, and invasion in breast cancer cells
Letitia A. Yearby, Terri Cunningham, Jacenta Matthews, KiTani Parker Lemieux. Xavier University of Louisiana, New Orleans, LA Poster Session
PO.TB06.05. Host-Tumor Interactions
Tue, Apr 19, 1:00 – 5:00 PM
Tue, Apr 19, 1:00 – 5:00 PM
3955/15 – Expression of cancer stem cell-associated proteins in exosomes derived from ascites of patients with advanced pancreatic cancer.
Takahiko Sakaue1, Hironori Koga1, Masaru Fukahori2, Yasuko Imamura3, Toru Nakamura1, Yoshinobu Okabe1, Yu Ikezono1, Fumitaka Wada1, Hideki Iwamoto1, Atsutaka Masuda1, Tomoyuki Ushijima1, Keisuke Miwa2, Tatsuyuki Kakuma4, Osamu Tsuruta1, Takuji Torimura1. 1Department of Medicine, Kurume University School of Medicine, Kurume City, Japan; 2Center for Multidisciplinary Treatment of Cancer, Kurume University Hospital, Kurume City, Japan; 3Liver Cancer Research Division, Kurume University Research Center for Innovative Cancer Therapy, Kurume City, Japan; 4Biostatistics Center, Kurume University, Kurume City, Japan Poster Session
PO.CL10.02. Circulating Biomarkers 3 / Immune Biomarkers
Tue, Apr 19, 1:00 – 5:00 PM
Tue, Apr 19, 1:00 – 5:00 PM
4113/10 – Pre-metastatic niche formation in palmitic acid and Caco2 BBE secreted exosomes treated HepG2 cells by the CD98-integrin-FAK pathway
Jenniffer L M Stetler, Brandon S. Canup, Hamed Laroui. Georgia State University, Atlanta, GA Poster Session
PO.TB04.02. Imaging and Therapeutics of Metastasis
Tue, Apr 19, 1:00 – 5:00 PM
Tue, Apr 19, 4:35 – 4:50 PM
4379 – Exosomes isolated from ovarian cancer cells transfer oncogenic features to the target cells promoting epithelial to mesenchymal transition
Miharu Kobayashi1, Laura Cohelo1, Dominic Guanzon2, Katherin Scholz-Romero1, Melissa Brown3, Richard Kline4, Li Li5, Gregory Rice1, Carlos Salomon1. 1Exosome Biology Laboratory, UQ Centre for Clinical Diagnostics, University of Queensland Centre for Clinical Research, Royal Brisbane and Women’s Hospital, The University of Queensland, Brisbane, Australia; 2School of Biomedical Sciences, Queensland University of Technology, Brisbane, Australia; 3Faculty of Medicine and Biomedical Sciences, The University of Queensland, Brisbane, Australia; 4Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Ochsner Clinic Foundation, New Orleans, LA; 5Translational Research, Colon and Rectal Surgery, the Ochsner Clinic Foundation, New Orleans, LA Minisymposium
MS.MCB01.01. Oncogenic Cell Signaling: Mechanisms and Translational Insight
Tue, Apr 19, 3:00 – 5:15 PM
Wed, Apr 20, 7:30 – 11:00 AM
5105/21 – Exosomes secreted by proinflammatory macrophages modulate breast cancer
Robert Bronislaw Bednarczyk, Neha Y. Tuli, Ghada Ben Rahoma, Rachana Maniyar, Abraham Mittelman, Raj K. Tiwari. New York Medical College, Valhalla, NY Poster Session
PO.TB06.08. Extracellular Microenvironment
Wed, Apr 20, 7:30 – 11:00 AM
Wed, Apr 20, 7:30 – 11:00 AM
5086/2 – Legumain-contained exosomes mediate remodeling of tumor extracellular matrix and protumor effects of TAMs
Long Shen1, Yuzhi Shi2, Jing Xun3, Chuanai Chen4, Lingfang Du4, Xiaoyue Tan1, Rong Xiang1. 1Key Lab of Tumor Microenvironment and Neurovascular Regulation, Nankai University, Tianjin, China; 2The 2011 Project Collaborative Innovation Center for Biological, School of Medicine, Nankai University, Tianjin, China; 3The International Collaborative Laboratory for Biological Medicine of the Ministry of Education, School of Medicine, Nankai University, Tianjin, China; 4Department of Immunology, Nankai University, Tianjin, China Poster Session
PO.TB06.08. Extracellular Microenvironment
Wed, Apr 20, 7:30 – 11:00 AM
Wed, Apr 20, 9:55 – 10:20 AM
Tumor exosomes determine pre-metastatic niches for organotropic metastasis
David C. Lyden. Weill Cornell Medical College of Cornell University, New York, NY Major Symposium
SY32. Pre-Metastatic Niches, Exosomes, and Tumor-Secreted Factors
Wed, Apr 20, 9:45 – 11:30 AM

Leave a Reply

Your email address will not be published. Required fields are marked *

*