Exosomes from cardiac injury have the potential to serve as biomarkers. Studying the contents of these exosomes and their physiological role in cardiac injury might reveal possible target and strategies to reduce cardiac injury. Exosomes from CMPCs and MSCs can stimulate angiogenesis and immune modulation. Exploiting these characteristics of exosomes from progenitors and enhancing their effect by cellular manipulation will have great potential in regenerative medicine as a therapeutic approach in itself or as a method to boost stem cell therapy.
Vrijsen K. (2013) Exosomes in Cardiac Injury. Epub by Uitgeverij BOXPress. [Thesis]