Featured Exosome Job – Extracellular Vesicles for Dystrophin Delivery in Duchenne Muscular Dystrophy

Department of Paediatrics, Le Gros Clark Building, South Parks Road, Oxford
Vacancy type: Research Grade 6: £29,176 – £34,804 p.a.
Vacancy ID: 145377 Closing Date: 18-MAR-2020
Contact Name: Chantelle Alderson Contact Email: chantelle.alderson@paediatrics.ox.ac.uk
Applications are invited for a Research Assistant to collaborate in the project entitled “Extracellular vesicles for dystrophin delivery in Duchenne Muscular Dystrophy”, under the direction of Professor Matthew Wood. The successful applicant will work with a postdoctoral research scientist, to generate and characterise extracellular vesicles and adeno-associated virus, perform a wide range of techniques to select lead compounds in vitro and test the lead candidates in vivo throughout the project.

The postholder is expected to collect and analyse data independently, adapt existing and develop new experimental protocols and collaborate in the preparation of scientific reports, within the guidance provided by senior colleagues. The appointed candidate will also be expected to carry out collaborative projects, provide advice and guidance to research students, where appropriate and ensure that all work is conducted safely.

The role requires the applicant to have a BSc or MSc degree in a relevant science subject, with relevant practical working experience in a laboratory. The applicant should be highly motivated and have the ability to communicate effectively with others, must have experience in general mammalian cell culture techniques and in a wide range of analytical tools of molecular biology (e.g. cloning, western blot, RT-qPCR). Knowledge in an area of research such as extracellular vesicles biology, nanotechnology, gene therapy or molecular medicine is extremely desirable. Experience with animal handling, administration of therapeutics into animals, techniques to isolate extracellular vesicles and AAV production are also extremely desirable.

Applicants who fulfil the majority of the criteria are encouraged to apply. The post is offered full-time and fixed-term until 28 February 2022 funded by Muscular Dystrophy Association.

The closing date for applications is 12.00 noon on Wednesday 18 March 2020. Interviews will be held as soon as possible thereafter.


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