With years of experience in the field of molecular and cell biology research, Creative Biolabs now introduces the cutting-edge exosome quantification platform covering a full list of technologies to detect and quantify exosomes in complex biological samples.
Exosomes are extracellular vesicles first described as such 30 years ago and since implicated in cell to cell communication and the transmission of disease states, and now are explored as a means of drug discovery. More and more studies have confirmed that exosomes can perform special functions by transferring specific substances such as nucleic acids, proteins, and lipids between cells. The analysis and detection of exosomes can assist in the early diagnosis, curative effect evaluation and prognosis analysis of diseases.
With years’ exploration in the field of exosome research, Creative Biolabs now unveils an innovative exosome quantification platform to help global clients detect and quantify exosomes in complex biological samples, where a variety of leading technologies are available.
- Nanoparticle Tracking Analysis
Creative Biolabs offers nanoparticle tracking analysis, which provides a combined analysis of Brownian motion via light scattering to count and size nanoparticles in a liquid suspension. Particles in suspension passed through a flow chamber and are illuminated using a laser source. The light scatter produced from this is recorded using a video camera.
- Tunable Resistive Pulse Sensing (TRPS)
TRPS detects the passage of individual particles through a pore in a membrane, and operates similarly to a Coulter counter. TRPS detection provides both concentration data and exosome size measurement.
- Vesicle Flow Cytometry
Flow cytometry detects particles suspended in a fluid by their interaction with a laser beam as they flow through a detection cell. Flow cytometry can take advantage of fluorescent-based immunostaining to provide an individual count of vesicles in solution characterized by the presence of specific markers.
- Surface Plasmon Resonance
Surface-based sensors are used to determine the vesicle concentration in solution by measuring the rate of arrival of the vesicles to a sensor surface under mass transport limited conditions.
- The enzyme-linked immunosorbent assay (ELISA)
ELISA captures exosomes at the bottom of a microwell and the amount of biomarker detected with antibodies generating a fluorescent or colorimetric signal, which is also feasible for multiple exosome marker analysis.
“Our solution is flexible and highly customized for every client. With accumulated experience on advantages and limitation of each technology to quantify exosomes, we are confident to provide a perfect design for various kinds of related programs.” introduced by a senior scientist at Creative Biolabs.
In addition, Creative Biolabs also provides a series of exosome capture & quantification kits allowing purification and quantification of circulating exosomes from human plasma, serum, urine, and cell media samples
Further information on exosome-related services and products at Creative Biolabs can be found on https://www.creative-biolabs.com/exosome.
About Creative Biolabs
Empowered by leading technology and years of experience in biomedical science, Creative Biolabs focuses on offering a full range of exosome-related services and products. The comprehensive services covering exosome sampling, analysis, manufacturing, and exosome-based application. The high-quality exosome-related products involving all aspects of exosome research, including exosome isolation and purification, exosome qualification, exosome antibody as well as exosome engineering.