Learn from NIH and Johns Hopkins scientists as they share the importance of accurate extracellular vesicle quantification in their research:
- Overview of EV Quantification Methods including Spectradyne’s nCS1
– Jean-Luc Fraikin, CEO Spectradyne
- Importance of EV concentration measurements in studies of macular degeneration
– Dr. Michael Paulaitis, Johns Hopkins University School of Medicine
- The importance of traceable measurement techniques for EV quantification
– Dr. Joshua Welsh, National Cancer Institute (NCI)
This webinar features two in-depth presentations from renowned researchers of Extracellular Vesicles (EVs).
First, Dr. Michael Paulaitis from The Center for Nanomedicine at the Wilmer Eye Institute Johns Hopkins University School of Medicine describes how accurate EV concentration measurements were important for a recent study of the role of mitochondria EVs in macular degeneration. In the presentation, EV concentrations are measured by Microfluidic Resistive Pulse Sensing (MRPS) and used to assess the potential of EV-bound microRNA as a biomarker for mitochondrial dysfunction.
Second, Dr. Joshua Welsh from The National Institutes of Health National Cancer Institute (Dr. Jennifer Jones Lab) makes a compelling case for standardization in reporting of Extracellular Vesicle concentration measurements to enable meaningful comparison of results between different measurement technologies and laboratories. Dr. Welsh presents a thorough and scientifically driven evolution in opinion of the best practices for ensuring traceability, by comparing measurements of EVs across different techniques including Nanoparticle Tracking Analysis (NTA), Transmission Electron Microscopy (TEM) and Microfluidic Resistive Pulse Sensing (MRPS).
An introduction and overview of various EV quantification methods is presented by Dr. Jean-Luc Fraikin, CEO of Spectradyne. Spectradyne’s nCS1 instrument uses Microfluidic Resistive Pulse Sensing to deliver fast, easy and affordable quantification of biological nanoparticles including extracellular vesicles and virus, using only 3 microliters of the sample. Visit Spectradyne’s website to learn more.