Extracellular particles (EPs) including extracellular vesicles (EVs) and exomeres play significant roles in diseases and therapeutic applications. However, their spatiotemporal dynamics in vivo have remained largely unresolved in detail due to the lack of...
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Large extracellular vesicles—a new frontier of liquid biopsy in oncology
Extracellular Vesicles (EVs) are emerging as pivotal elements in cancer. Many studies have focused on the role of Small- (S)-EVs but in recent years Large-(L)-EVs have progressively gained increasing...
Read More »Different precipitation-based methods impact extracellular vesicles biomarker analysis
Extracellular vesicles(EVs) is an emerging approach of cancer liquid biopsy. Although the precipitation-based method with commercial kits has gained popularity as the second most commonly used technique, these protocols vary tremendously with many...
Read More »BloodPAC Publishes FDA-Reviewed Validation Protocols for Liquid Biopsy
The Blood Profiling Atlas in Cancer Consortium (BloodPAC) published “Generic Protocols for the Analytical Validation of Next-Generation Sequencing-Based ctDNA Assays: A Joint Consensus Recommendation of the BloodPAC’s Analytical Variables Working ...
Read More »Exosomes – A potential therapeutic tool targeting communications between tumor cells and macrophages
Exosomes comprise extracellular vesicles (EVs) with diameters between 30 and 150 nm. They transfer proteins, RNA, and other molecules from cell to cell, playing an important role in the interactions ...
Read More »Long single-stranded DNAs for electrochemical detection of exosomal microRNAs
Exosomal microRNAs (miRNAs) have been explored as an extremely promising biomarker of liquid biopsy for the diagnosis, treatment and prognosis of diseases such as cancer, in which sensitive and selective detection is significant. Researchers at...
Read More »Researchers raise questions about the routine applicability of conventional flow cytometers for EV analysis
Intense research is being conducted using flow cytometers available in clinically oriented laboratories to assess extracellular vesicles (EVs) surface cargo in a variety of diseases. Using EVs of...
Read More »Researchers develop tiny tweezers to catch exosomes
In 2018, one-half of the Nobel Prize was awarded to Arthur Ashkin, the physicist who developed optical tweezers, the use of a tightly focused laser beam to isolate and move micron-scale objects (the size of...
Read More »Jobs
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Doctoral thesis research position available – Extracellular Vesicles and the Blood-Brain Barrier
The Austrian Institute of Technology is Austria’s largest research and technology organisation and an international player in applied research for...
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Featured Exosome Job – Scientist, Translational Biology
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Featured Exosome Job – Vice President, Head of Analytical Development
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Featured Exosome Job – facilitate the intracellular delivery and extracellular transport of gene modulating and editing technologies
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Featured exosome job – Programmer/Analyst supporting the Extracellular RNA Communications Consortium
Industry News
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Evox Therapeutics completes £69.2 million Series C financing
Financing round significantly oversubscribed by both new and existing investors Proceeds enable advancement of our exosome therapeutics into the clinic and expansion of our world-leading exosome...
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Ciloa’s project based on exosomes customization is among the 11 winners of the “Sanofi iTech Awards”
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VivaZome and La Trobe University enter new research collaboration to develop exosome therapeutics
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Codiak Announces Pricing of $57.8 Million Public Offering of Common Stock
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Exosome-based liquid biopsies in cancer