United Therapeutics – Research Triangle Park, NC
Position Overview:
Conduct and assist in research efforts to develop tissue-based regenerative medicine products for the treatment of pulmonary hypertension and other lung diseases.
Key Accountabilities / Responsibilities:
- Routinely perform large-scale cell culture, including stem/progenitor cell culture, to support product development activities
- Routinely perform bioanalytical assays to characterize cellular phenotypes (Western Blot, qPCR, flow cytometry, immunohistochemistry)
- Conduct process development studies to improve yield, purity, and quality of cell-secreted products
- Routinely perform analytical assays to characterize the molecular composition of cell-secreted products
- Assist in the development and execution of cell-based potency assays for candidate products
- Author laboratory procedures and protocols for the production and analysis of cell-secreted products
- Follow prescribed laboratory methods and protocols under GLP -like conditions
- Record laboratory data in the in-house data management system(s)
- Regularly present and discuss data with laboratory staff and program leaders
Minimum Requirements:
- Bachelor’s Degree in Biology, Cell or Molecular Biology, or Biomedical Sciences
- 2-5 years of post-baccalaureate experience in Biology, Cellular and Molecular Biology, or Biomedical Sciences
- Experience with stem or progenitor cell culture, aseptic technique, and/or flow cytometry
- Strong skills in molecular assays, cellular assays, and/or fluorescence microscopy
Preferred Knowledge, Skills, and Abilities:
- Analytical skillset, with focus on macromolecular compositions (e.g. RNA, protein, lipids); FPLC experience a plus
- Ability to work efficiently in a team setting
- Ability to work with a diverse set of co-workers
- Strong written and oral communication skills
- Ability to independently follow experimental methods and protocols
- Ability to organize data
- Highly self-motivated
- Ability to initiate routine and day-to-day tasks
United Therapeutics Corporation is an Equal Opportunity/Affirmative Action Employer – EOE Minorities / Females / Protected Veterans / Individuals with Disabilities
Requisition ID: R00104
APPLY