United Therapeutics Research Technician – Exosomes in Research Triangle Park, North Carolina
Position Overview:
Conduct and assist in research efforts to develop tissue-based regenerative medicine products for the treatment of pulmonary hypertension and other lung diseases.
Key Accountabilities / Responsibilities:
- Routinely perform large-scale cell culture, including stem/progenitor cell culture, to support product development activities
- Routinely perform bioanalytical assays to characterize cellular phenotypes (Western Blot, qPCR, flow cytometry, immunohistochemistry)
- Conduct process development studies to improve yield, purity, and quality of cell-secreted products
- Routinely perform analytical assays to characterize the molecular composition of cell-secreted products
- Assist in the development and execution of cell-based potency assays for candidate products
- Author laboratory procedures and protocols for the production and analysis of cell-secreted products
- Follow prescribed laboratory methods and protocols under GLP -like conditions
- Record laboratory data in the in-house data management system(s)
- Regularly present and discuss data with laboratory staff and program leaders
Minimum Requirements:
- Bachelor’s Degree in Biology, Cell or Molecular Biology, or Biomedical Sciences
- 0-5 years of post-baccalaureate experience in Biology, Cellular and Molecular Biology, or Biomedical Sciences
- Experience with stem or progenitor cell culture, aseptic technique, and/or flow cytometry
- Strong skills in molecular assays, cellular assays, and/or fluorescence microscopy
Preferred Knowledge, Skills, and Abilities:
- Analytical skillset, with focus on macromolecular compositions (e.g. RNA, protein, lipids); FPLC experience a plus
- Ability to work efficiently in a team setting
- Ability to work with a diverse set of co-workers
- Strong written and oral communication skills
- Ability to independently follow experimental methods and protocols
- Ability to organize data
- Highly self-motivated
- Ability to initiate routine and day-to-day tasks
United Therapeutics Corporation is an Equal Opportunity/Affirmative Action Employer – EOE Minorities / Females / Protected Veterans / Individuals with Disabilities
United Therapeutics Corporation is a biotechnology company focused on the development and commercialization of unique products to address the unmet medical needs of patients with chronic and life-threatening conditions.We currently have five approved products on the market, and a long-term mission of providing an unlimited supply of transplantable organs for those who need them! Our employees can be found collaborating across the United States, Europe and Asia. As a group, we are relentless in our pursuit of “medicines for life” and continue to research and develop treatments for cardiovascular and pulmonary diseases, pediatric cancers, and other orphan diseases.
We challenge our employees with innovative and revolutionary projects, offer an environment which fosters high level job performance, and provide state of the art facilities in which to flourish. This is what makes United Therapeutics a stimulating place to work.We strive to be an organization that engages the minds, hearts, and most spirited efforts of each of our employees. Our sense of purpose transforms what we do from work into mission, occupation into vocation, and achievement into success.
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