Recent Papers Covering Exosome Function

Exosomes participate in the alteration of muscle homeostasis during lipid-induced insulin resistance in mice.

Aswad H, Forterre A, Wiklander OP, Vial G, Danty-Berger E, Jalabert A, Lamazière A, Meugnier E, Pesenti S, Ott C, Chikh K, El-Andaloussi S, Vidal H, Lefai E, Rieusset J, Rome S.
Diabetologia. 2014 Jul 30. [Epub ahead of print]

Exosomes mediate drug resistance transfer in MCF-7 breast cancer cells and a probable mechanism is delivery of P-glycoprotein.

Lv MM, Zhu XY, Chen WX, Zhong SL, Hu Q, Ma TF, Zhang J, Chen L, Tang JH, Zhao JH.
Tumour Biol. 2014 Jul 31. [Epub ahead of print]

Exosomes induce transforming growth factor beta pathway dysregulation in hepatocytes: a novel paradigm for obesity-related liver disease.

Koeck ES, Iordanskaia T, Sevilla S, Ferrante SC, Hubal MJ, Freishtat RJ, Nadler EP.
J Surg Res. 2014 Jul 7. pii: S0022-4804(14)00628-3. doi: 10.1016/j.jss.2014.06.050. [Epub ahead of print]

Exosomes inhibit in vitro tumor growth: A new approach for drug delivery.

Pascucci L, Coccè V, Bonomi A, Ami D, Ceccarelli P, Ciusani E, Viganò L, Locatelli A, Sisto F, Doglia SM, Parati E, Bernardo ME, Muraca M, Alessandri G, Bondiolotti G, Pessina A.
J Control Release. 2014 Jul 30. pii: S0168-3659(14)00523-9. doi: 10.1016/j.jconrel.2014.07.042. [Epub ahead of print]