Target ALS announced today the grantees receiving funding for new projects focused on ALS biomarker discovery and development, resulting from a call for proposals issued in the spring. In accordance with the requirements of the Target ALS grantmaking process, collaboration between ...
Read More »Brain exosomes from blood samples allow earlier diagnosis of ALS
Exosomes, microscopic packets containing genetic material, are shed by tissues into the blood. By sequencing microRNA within exosomes originating in the brain, it is now possible to definitively distinguish blood samples of ALS patients from healthy controls...
Read More »Featured Exosome Job – Modulation of gene expression profiling in a murine model of ALS after asc-exosomes treatment
Employer – University of Verona – Department of Neurosciences, Biomedicine and Movement Location – Italy Posted – November 28 2017 In the present project we would like to characterize the content of exosomes, in terms of proteins and RNAs, to ...
Read More »Extracellular Vesicles in Brain Tumors and Neurodegenerative Diseases
Extracellular vesicles (EVs) can be classified into apoptotic bodies, microvesicles (MVs), and exosomes, based on their origin or size. Exosomes are the smallest and best characterized vesicles which derived from the endosomal system. These vesicles are released from many different ...
Read More »DPRs Spread Between Cells via Exosomes, but Pathogenic Significance Remains Unclear
from ALS Research Forum by Richard Robinson – Dipeptide repeat proteins (DPRs) translated from the C9ORF72 expansion spread from cell to cell in vitro, including via exosomes, according to a study in the October 11 Cell Reports. The finding hints ...
Read More »