Extracellular vesicles (EVs) can be classified into apoptotic bodies, microvesicles (MVs), and exosomes, based on their origin or size. Exosomes are the smallest and best characterized vesicles which derived from the endosomal system. These vesicles are released from many different ...
Read More »Student Wins Nation’s Top High School Science Competition for Work with Exosomes
Indrani Das, 17, a student at Bergen County Academies, developed a new approach to treating neurodegenerative diseases ORADELL, N.J. — A Bergen County Academies student has won the nation’s oldest science and math competition and $250,000 for developing a new ...
Read More »Exosomes and Antibodies Tie Plasma Aβ and Tau to Alzheimer’s
While changes in cerebrospinal fluid Aβ and tau reliably flag the onset of Alzheimer’s disease, plasma levels of these proteins have remained frustratingly uninformative. At the annual Society for Neuroscience conference, held November 12-16 in San Diego, speakers once again ...
Read More »Astrocytes and Exosomes Implicated in Protein Propagation
Alzfoum – Many researchers now believe that misfolded proteins spread from cell to cell across the brain, corrupting normal proteins as they go, yet exactly how this propagation would happen remains unclear. At the Society for Neuroscience annual meeting, held ...
Read More »Exosomes that trap amyloid appear to also contribute to Alzheimer’s
Vesicles, fluid-filled sacs that brain cells make to trap amyloid, a hallmark of Alzheimer’s, appear to also contribute to the disease, scientists report. Reducing the production of these vesicles, called exosomes, could help reduce the amount of amyloid and lipid ...
Read More »Exosome-Derived Biomarker Predicts Likelihood of Developing Alzheimer’s Disease
from BiotechDaily International – Neurological disease researchers have developed a method for using a biomarker in the blood to predict the likelihood of mild cognitive impairment (MCI) progressing into full-blown Alzheimer’s disease (AD). “MCI is often a transitional stage between ...
Read More »Cellular vessels predict likelihood of developing dementia
Blood-based neuronally-derived exosomes carry tell-tale proteins that could help forecast transition from mild cognitive impairment to Alzheimer’s disease Researchers at University of California San Diego School of Medicine say tiny micro-vesicle structures used by neurons and other cells to transport ...
Read More »Surprising finding provides more support for Alzheimer’s being an autoimmune disease
Brain levels of the lipid ceramide are high in Alzheimer’s disease, and now scientists have found increased levels of an antibody to the lipid in their disease model. While some members of this lipid family are a plus in ...
Read More »Emerging roles of extracellular vesicles in the nervous system
Information exchange executed by extracellular vesicles, including exosomes, is a newly described form of intercellular communication important in the development and physiology of neural systems. These vesicles can be released from cells, are packed with information including signaling proteins and ...
Read More »Alzheimer’s Test Detects Disease Decade Ahead of Onset
from Bloomberg News By Megan Scudellari A new blood test for Alzheimer’s appears to detect the disease as many as 10 years before clinical diagnosis is possible — far sooner than other tests in development. The test, described publicly for ...
Read More »