Tag Archives: Amyotrophic Lateral Sclerosis

Target ALS announced today the grantees receiving funding for new projects focused on ALS biomarker discovery and development, resulting from a call for proposals issued in the spring. In accordance with the requirements of the Target ALS grantmaking process, collaboration between ...

Extracellular vesicles, small reservoirs that carry various biomolecules, have gained significant interest from the clinical field in recent years based on the diagnostic, therapeutic and prognostic...

Exosomes are involved in intracellular communication and contain proteins, mRNAs, miRNAs, and signaling molecules. Exosomes were shown to act as neuroinflammatory mediators involved in neurodegenerative diseases including Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS). Brain aging has ...

Extracellular vesicles (EVs) can be classified into apoptotic bodies, microvesicles (MVs), and exosomes, based on their origin or size. Exosomes are the smallest and best characterized vesicles which derived from the endosomal system. These vesicles are released from many different ...

from ALS Research Forum by Richard Robinson – Dipeptide repeat proteins (DPRs) translated from the C9ORF72 expansion spread from cell to cell in vitro, including via exosomes, according to a study in the October 11 Cell Reports. The finding hints ...