Exosomes are endosome-derived membrane vesicles carrying proteins and nucleic acids that are involved in cellular functions such as intercellular communication, protein and RNA secretion, and antigen presentation, and therefore serve as potential biomarkers for many diseases including cancer. Since exosomes ...
Read More »Improved vaccine efficacy of tumor exosome compared to tumor lysate loaded dendritic cells
Leukemia immunotherapy frequently does not meet expectation, one of the handicaps being tumor exosome (TEX)-promoted immunosuppression. Researchers at the University Hospital of General Surgery asked, using the mouse myeloid leukemia WEHI3B and the renal cell carcinoma line RENCA, whether dendritic ...
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