By analyzing the nanomechanical properties of extracellular vesicles using atomic force microscopy and deep learning, researchers achieved 96% accuracy in identifying lung cancer gene mutations, paving the way for precise, non-invasive diagnostics...
Read More »Method for mid-IR spectroscopy of extracellular vesicles at the subvesicle level
A new protocol using atomic force microscopy infrared spectroscopy (AFM-IR) enables the analysis of extracellular vesicles at the single-vesicle level, providing valuable insights into their chemical composition and potential role in immune system...
Read More »High-Speed AFM reveals the molecular dynamics of HA and its interaction with exosomes
Researchers at Kanazawa University report in Nano Letters a high-speed atomic force microscopy study on a biological event that occurs when a flu virus...
Read More »A step closer to a cure for adult-onset diabetes – could “sick” exosomes be to blame
In healthy people, exosomes – tiny structures secreted by cells to allow intercellular communication – prevent clumping of the protein that leads to type 2 diabetes. Exosomes in patients with the disease don’t have the same ability. This discovery by ...
Read More »Atomic force microscopy analysis of extracellular vesicles
Extracellular vesicles (EVs) are small vesicles ensuring transport of molecules between cells and throughout the body. EVs contain cell type-specific signatures and have been proposed as biomarkers in a variety of diseases. Their small size (<1 μm) and biological and ...
Read More »Immunoaffinity based methods are superior to kits for purification of prostate derived extracellular vesicles from plasma samples
The ability to isolate extracellular vesicles (EVs) such as exosomes or microparticles is an important method that is currently not standardized. While commercially available kits offer purification of EVs from biofluids, such purified EV samples will also contain non-EV entities ...
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