Exosomes are nanoscale vesicles distinguished by characteristic biophysical and biomolecular features; current analytical approaches, however, remain univariate. Here, researchers from the National University of Singapore develop a dedicated platform for multiparametric exosome analysis—through simultaneous biophysical and biomolecular evaluation of the ...
Read More »Liquid Biopsy as Novel Tool in Precision Medicine
In recent years, there has been an increase in knowledge of cancer, accompanied by a technological development that gives rise to medical oncology. An instrument that allows the...
Read More »Rapid and label-free isolation of small extracellular vesicles from biofluids utilizing a novel insulator based dielectrophoretic device
Exosomes are nano-scale membrane-encapsulated vesicles produced by the majority of cells and have emerged as a rich source of biomarkers for a wide variety of diseases. Although many approaches have been developed for exosome isolation from biofluids, most of them ...
Read More »Avalon GloboCare CEO David Jin to unveil exosome commercialization plan at China confab
Avalon GloboCare announced Thursday that CEO David Jin will unveil the launch of the company’s new commercialization plan for its exosome...
Read More »ExoTIC – The Exosome Total Isolation Chip
Circulating tumor-derived extracellular vesicles (EVs) have emerged as a promising source for identifying cancer biomarkers for early cancer detection. However, the clinical utility of EVs has thus far been limited by the fact that most EV isolation methods are tedious, ...
Read More »ExRNA in Biofluids as Biomarkers for Brain Tumors
EV RNAs have tremendous clinical potential as diagnostic, subtype-defining, and prognostic biomarkers in GBM. The identification of new EV RNA targets and validation of existing EV RNA targets will be accelerated by large-scale biorepositories established for clinic sample warehousing and ...
Read More »Molecular screening of cancer-derived exosomes by surface plasmon resonance (SPR) spectroscopy
Exosomes are nanovesicles shed by cells into their microenvironment and carry the molecular identity of their mother cells. These vesicles are actively involved in intercellular communication under physiological conditions and ultimately in the spread of various diseases such as cancer. ...
Read More »Upcoming Webinar – miRNA profiling of biofluid samples
11:00 a.m. EST; 4:00 p.m. GMT Wednesday, October 15, 2014 This webcast presents an in depth research on miRNA biomarker development. It integrates PCR-based system that reduces the amount of sample required for full miRNome profiling and provides unparalleled reproducibility ...
Read More »Circulating miRNAs: cell-cell communication function?
Nuclease resistant extracellular miRNAs have been found in all known biological fluids. The biological function of extracellular miRNAs remains questionable; however, strong evidence suggests that these miRNAs can be more than just byproducts of cellular activity. Some extracellular miRNA species ...
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