Over the past decade, extracellular vesicles and particles (EVPs) have emerged as critical mediators of intercellular communication, participating in...
Read More »Urinary Exosomal miRNAs as biomarkers of bladder cancer
Bladder cancer (BC) is one of the most common malignancies globally. Early diagnosis of it can significantly improve patients’ survival and quality of life. Urinary exosomes (UEs)-derived miRNAs...
Read More »Biomarkers of cancer cell-derived extracellular vesicles from liquid biopsies
Tumor-secreted extracellular vesicles (EVs) are the main mediators of cell-cell communication, permitting cells to exchange proteins, lipids, and...
Read More »UH researcher receives NIH grant to detect cancer biomarkers in blood by counting exosomes
University of Houston Researcher Receives $2.7M Grant to Develop Test with ‘Unprecedented Early Detection Power’ Liquid biopsy...
Read More »Liquid biopsy-based exo-oncomiRNAs can predict prostate cancer aggressiveness
Liquid biopsy-based biomarkers, including microRNAs packaged within extracellular vesicles, are promising tools for patient management. The cytokine tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is related to PCa progression and is found in the semen of patients with PCa. ...
Read More »Emerging roles of exosomal circular RNAs in cancer
Circular RNA (circRNA) is a type of non-coding RNA that forms a covalently closed continuous loop. The expression pattern of circRNA varies among cell types and tissues, and many circRNAs are aberrantly expressed in various cancers. Aberrantly expressed circRNAs have ...
Read More »Ymir Genomics & (OHSU) announce a licensing agreement and patent application covering miRNA biomarkers discovered utilizing Ymir’s extracellular vesicle isolation technology
Ymir Genomics LLC (Ymir) and the Oregon Health & Science University (OHSU) Knight Cancer Institute today announced a licensing agreement and filed patent application that seeks to protect and promote newly-discovered high value urinary biomarkers for detecting cirrhosis and/or hepatocellular ...
Read More »Tear exosomes – a potential source of diagnostic and prognostic biomarkers for metastatic breast cancer
Exosomes are produced by normal and cancer cells. Exosomes are found in the serum of cancer patients and have been used for diagnosis and prognosis. Recently tears from non-cancer patients have been found to contain exosomes. In the present report ...
Read More »Unravelling the proteomic landscape of extracellular vesicles in prostate cancer by density-based fractionation of urine
Extracellular vesicles (EV) are increasingly being recognized as important vehicles of intercellular communication and promising diagnostic and prognostic biomarkers in cancer. Despite this enormous...
Read More »Gold nanoparticles detect extracellular vesicles from cancer cells
A novel blood test that uses gold nanoparticles to detect cancer has also been shown to identify signals released by cancer cells which could result...
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