Circular RNA (circRNA) is a type of non-coding RNA that forms a covalently closed continuous loop. The expression pattern of circRNA varies among cell types and tissues, and many circRNAs are aberrantly expressed in various cancers. Aberrantly expressed circRNAs have ...
Read More »Ymir Genomics & (OHSU) announce a licensing agreement and patent application covering miRNA biomarkers discovered utilizing Ymir’s extracellular vesicle isolation technology
Ymir Genomics LLC (Ymir) and the Oregon Health & Science University (OHSU) Knight Cancer Institute today announced a licensing agreement and filed patent application that seeks to protect and promote newly-discovered high value urinary biomarkers for detecting cirrhosis and/or hepatocellular ...
Read More »Tear exosomes – a potential source of diagnostic and prognostic biomarkers for metastatic breast cancer
Exosomes are produced by normal and cancer cells. Exosomes are found in the serum of cancer patients and have been used for diagnosis and prognosis. Recently tears from non-cancer patients have been found to contain exosomes. In the present report ...
Read More »Unravelling the proteomic landscape of extracellular vesicles in prostate cancer by density-based fractionation of urine
Extracellular vesicles (EV) are increasingly being recognized as important vehicles of intercellular communication and promising diagnostic and prognostic biomarkers in cancer. Despite this enormous...
Read More »Gold nanoparticles detect extracellular vesicles from cancer cells
A novel blood test that uses gold nanoparticles to detect cancer has also been shown to identify signals released by cancer cells which could result...
Read More »Recent achievements in exosomal biomarkers detection by nanomaterials-based optical biosensors
Exosomal biomarkers including tumor-derived exosomes, exosomal surface proteins and exosomal nucleic acids have emerged as one of the most important and general cancer biomarkers in modern...
Read More »Veravas and Tymora Collaborate on Early Detection Alzheimer’s Testing
Veravas, Inc. and Tymora Analytical Operations, LLC announced today that they have entered into a strategic alliance to explore the integration of their respective technologies. Veravas is an emerging diagnostic company focused on proprietary sample preparation products and new diagnostic tests. Tymora’s focus ...
Read More »Extracellular vesicles in chronic obstructive pulmonary disease (COPD)
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterised by chronic inflammation and significant airflow obstruction that is not fully reversible, and is one of the leading causes of morbidity and mortality worldwide. Extracellular...
Read More »A hybridization chain reaction based assay for fluorometric determination of exosomes
Exosomes represent a new generation of biomarkers for the early diagnosis of hepatic carcinoma. Researchers from Tongji Medical College have developed a fluorometric assay that is based on the hybridization chain reaction and magnetic...
Read More »Extracellular vesicles – a novel source of biomarkers in liquid biopsies for monitoring cancer progression and drug resistance
Cancer-derived extracellular vesicles (EVs) have been detected in the bloodstream and other biofluids of cancer patients. They carry various tumor-derived molecules such as mutated DNA and RNA fragments...
Read More »