Current cancer diagnostic methods are challenged by low sensitivity, high false positive rate, limited tumor information, uncomfortable or invasive procedures, and high cost. Liquid biopsy that analyzes circulating...
Read More »A new plasmonic biosensor can detect diseased exosomes even by the naked eye
Exosomes, important indicators of health conditions, are cell-derived vesicles that are present in blood and urine. A rapid analysis by biosensors helps...
Read More »A ratiometric electrochemical biosensor for the exosomal microRNAs detection
Sensitive and selective detection of microRNAs (miRNAs) in cancer cells derived exosomes have attracted rapidly growing interest owing to their potential in diagnostic and prognostic applications. Here, researchers from the Fujian Agriculture and Forestry University design a ratiometric electrochemical biosensor ...
Read More »Antibiotic-induced release of exosomes with surface-associated DNA
Recently, biological roles of extracellular vesicles (which include among others exosomes, microvesicles and apoptotic bodies) have attracted substantial attention in various fields of biomedicine. Here, researchers at Semmelweis University investigated the impact of sustained exposure of cells to the fluoroquinolone ...
Read More »Direct detection of tumor-derived extracellular vesicles by self-assembly gold nanoisland-LSPR biosensor
Extracellular vesicles (EVs) are abundant in various biological fluids including blood, saliva, urine, as well as extracellular milieu. Accumulating evidence has indicated that EVs, which contain functional proteins and small RNAs, facilitate intercellular communication between neighbouring cells, and are critical ...
Read More »A biosensor is able to detect tumors at early stages
IMAGE: Tumor suppressor p53 trimer and DNA fragment. Credit: Cho, Y., Gorina, S., Jeffrey, P.D., Pavletich, N.P.; Astrojan. Before a malignant tumor is developed, the immune system tries to fight against proteins that are altered during their formation, producing certain cancer ...
Read More »Nanochip to isolate exosomes makes IBM brain trust’s 5 in 5 list
For the last decade, IBM has asked its brain trust of scientists and researchers to pick the five hottest of the hot technologies on the cusp of broad adoption. This year’s 5 in 5 list focuses on how advances in ...
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