The results of a recent research project conducted jointly by Cardiocentro Ticino and the EOC Neurocentro deliver a message of hope in the fight against Parkinson’s disease, as well as providing encouraging news for the USI Faculty of Biomedical Sciences. ...
Read More »Rapid and efficient isolation of exosomes by clustering and scattering
Tumor-derived extracellular vesicles (EVs) have become important biomarkers of liquid biopsies for precision medicine. However, the clinical application of EVs has been limited due to the lack of EV isolation practical technology applicable to clinical environments. Researchers at the Korea ...
Read More »Researchers Build “Liquid Biopsy” Chip that Detects Metastatic Cancer Cells in a Drop of Blood
More effective than existing microfluidic devices, the breakthrough technology paves the way for clinical development of simple blood tests for many cancers. A chip developed by mechanical engineers at Worcester Polytechnic Institute (WPI) can trap and identify metastatic cancer cells ...
Read More »Researchers decipher stem cell messages in blood vessel formation
Findings may lead to novel treatment approaches for peripheral artery disease (SACRAMENTO, Calif.) — An international collaboration between UC Davis and Swedish scientists has resulted in the first comprehensive characterization of a recently discovered cell-to-cell communication system used by stem ...
Read More »Isolation of Exosomes from Blood Plasma – Qualitative and Quantitative Comparison of Ultracentrifugation and Size Exclusion Chromatography Methods
Exosomes are emerging targets for biomedical research. However, suitable methods for the isolation of blood plasma-derived exosomes without impurities have not yet been described. Therefore, researchers from Semmelweis University, Hungary investigated the efficiency and purity of exosomes isolated with potentially ...
Read More »RNA-seq for blood-based pan-cancer diagnostics
from Nature Reviews Genetics by Liesbet Lieben A systemic, minimally invasive diagnostic test to determine whether an individual has cancer could greatly improve cancer prognosis by facilitating early diagnosis and improving monitoring. However, the use of blood-based ‘liquid biopsies’ is ...
Read More »Accessing Genetic Information with Liquid Biopsies
Recent scientific advances in understanding circulating tumor cells, cell-free DNA/RNA, and exosomes in blood have laid a solid foundation for the development of routine molecular ‘liquid biopsies’. This approach provides non-invasive access to genetic information – somatic mutations, epigenetic changes, ...
Read More »Exosomes – A Major Phenomenon Flying Under the Radar
from The Cell Culture Dish – A guest blog by William G. Whitford, Strategic Solutions Leader, BioProcess, GE Healthcare Life Sciences Exosomes in Nature It was discovered some time ago that eukaryotic cells regularly secrete such structures as microvesicles, macromolecular ...
Read More »Norgen Biotek Corp Launches over 15 Novel Kits for the Isolation of High-Quality Circulating Nucleic Acids from Blood, Plasma, Serum and Urine
THOROLD, ON, Sept. 28, 2015 /CNW/ – Norgen Biotek Corp., an innovative privately held Canadian biotechnology company focusing primarily on advancing powerful tools for nucleic acids (NA) and protein purification, today announced the launch of over 15 novel kits for ...
Read More »Exosomes – emerging roles in communication between blood cells and vascular tissues
Microvesicles, in general, and exosomes together with their delivered content in particular, are now being widely recognized as key players in atherosclerosis. This reveiw focuses on the roles of exosomes and discuss their emergent role in mediating activation and response ...
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