With age, the form and function of our bones and muscles drop off, putting us as increased risk for frailty and falls. Now researchers at the Medical College of Georgia at Augusta University are dissecting just what happens to the ...
Read More »Characterization of Regulatory Extracellular Vesicles from Osteoclasts
Extracellular vesicles (EVs), which include exosomes and ectosomes/microvesicles, have emerged as important intercellular regulators. EVs can interact with surface receptors of target cells and can transport luminal components, including messenger RNAs (mRNAs), microRNAs, and enzymes, to the cytosol of the ...
Read More »Could matrix vesicles be anchored exosomes?
Schematic diagram of pathways for formation of mineralizing exosomes (matrix vesicles). Numerous studies have documented that matrix vesicles are unique extracellular membrane-bound microparticles that serve as initial sites for mineral formation in the growth plate and most other vertebrate mineralizing ...
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