Researchers used high-speed atomic force microscopy to measure antibody binding to PD-L1 on individual extracellular vesicles, revealing differences in protein accessibility that conventional measurements may miss...
Read More »Clinical trial to evaluate blood test for early detection of breast cancer
USC researchers are evaluating a blood test that detects tumor-associated extracellular vesicles and rare cancer cells, potentially improving early breast cancer detection alongside mammography...
Read More »Biomarkers for the early detection of breast cancer
Extracellular vesicles in blood carry molecular signatures from their cells of origin, and new label-free methods may improve their use as biomarkers for cancer detection...
Read More »MetroHealth Scientist Awarded $3.3 Million NIH Grant to Study How Breast Cancer Spreads
MetroHealth Research Institute scientist Khalid Sossey-Alaoui, PhD, has been awarded a five-year, $3.3 million grant from the National Institutes of...
Read More »Extracellular vesicle integrins show potential for detecting early breast cancer and bone metastasis
Plasma extracellular vesicles carrying integrins αV and β3 show potential as biomarkers for early breast cancer detection and identifying disease associated..
Read More »Spatial-EV-seq provides a tissue map of extracellular vesicles
Spatial-EV-seq maps extracellular vesicles within intact tissues, revealing how their location and movement can shape immune activity and cellular communication in the tumor microenvironment...
Read More »Spatial-EV-seq maps extracellular vesicles within tissues
Spatial-EV-seq combines extracellular vesicles with transcriptomics to map EV-cell communication directly within tissues, providing new opportunities for precision diagnostics and cancer research....
Read More »Liquid biopsy predicts response to breast cancer immunotherapy
Extracellular vesicles and blood-based RNA profiling reveal immune responses during treatment, helping predict immunotherapy outcomes and guide personalized strategies in breast cancer patients...
Read More »Early release of tumor exosomes in ductal carcinoma in situ
Tumor derived extracellular vesicles spread systemically during early DCIS, altering distant organ gene expression before invasion and highlighting exosomes as potential drivers of premetastatic...
Read More »Researchers aim to disrupt breast cancer line of communication and prevent spread
Neutrophil-derived extracellular vesicles shaped by a cholesterol metabolite drive breast cancer cells toward chemoresistance and metastasis, revealing...
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