University of Toronto researchers performed in vitro and in vivo experiments to investigate the role of the circular RNA circSKA3 in tumor development...
Read More »Plasma-derived extracellular vesicles circular RNAS serve as biomarkers for breast cancer diagnosis
Breast cancer is the second cause of cancer-associated death among women and seriously endangers women’s health. Therefore, early identification of breast cancer would be beneficial to...
Read More »Proteomic landscape of exosomes reveals the functional contributions of CD151 in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer. Patients with TNBC have poor overall survival due to limited molecular therapeutic targets. Recently, exosomes have...
Read More »Identification of a novel RNA aptamer that selectively targets breast cancer exosomes
Breast cancer is a leading cause of cancer mortality in women. Despite advance in its management, the identification of new options for early stage...
Read More »Microfluidic human liver-chip to investigate the roles of breast cancer-derived extracellular vesicles
A new study, affiliated with UNIST has unveiled the mechanisms involved in the liver metastasis of breast cancer, thanks to the three-dimensional (3D) organ-on-a-chip that mimics human liver functions...
Read More »Breast cancer cells use message-carrying extracellular vesicles to send oncogenic stimuli to neighboring normal cells
According to a study by The Wistar Institute, breast cancer cells starved for oxygen send out messages that induce oncogenic changes in surrounding normal epithelial cells. These messages are packaged into particles called extracellular vesicles (EVs) and reprogram mitochondrial shape ...
Read More »Tear exosomes – a potential source of diagnostic and prognostic biomarkers for metastatic breast cancer
Exosomes are produced by normal and cancer cells. Exosomes are found in the serum of cancer patients and have been used for diagnosis and prognosis. Recently tears from non-cancer patients have been found to contain exosomes. In the present report ...
Read More »Anticancer effect of physical activity is mediated by modulation of extracellular microRNA in blood
Researchers at the University of Genoa aimed to explore the involvement of miRNAs in beneficial effects exerted by physical activity in breast cancer prevention.The levels of extracellular miRNAs were evaluated in blood plasma before and after structured...
Read More »Isolation of breast cancer-derived nanovesicles by immunomagnetic separation and electrochemical immunosensing
Exosomes are cell-derived nanovesicles released into biological fluids, which are involved in cell-to-cell communication. The analysis of the content and the surface of the exosomes allow conclusions about the...
Read More »Microfluidic device for on-chip isolation and detection of circulating exosomes in blood of breast cancer patients
Tumor-derived circulating exosomes have been recognized as a promising biomarker source for cancer diagnosis via a less invasive procedure. The integration of isolation and detection of exosomes in...
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