Exosomes are biomolecular nanostructures released from cells. They carry specific biomolecular information and are mainly researched for their exquisite properties as a biomarker source and delivery system. Researchers from the Bellvitge Biomedical Research Institute introduce exosomes in the context of other ...
Read More »Exosomes in Cancer Liquid Biopsy
The important challenge about cancer is diagnosis in primary stages and proper treatment. Although classical clinico-pathological features of the tumor have major prognostic value, the advances in diagnosis and treatment are indebted to discovery of molecular biomarkers and control of ...
Read More »Exosomal microRNAs in giant panda (Ailuropoda melanoleuca) breast milk
The physiological role of miRNAs is widely understood to include fine-tuning the post-transcriptional regulation of a wide array of biological processes. Extensive studies have indicated that exosomal miRNAs in the bodily fluids of various organisms can be transferred between living ...
Read More »Breast milk-derived exosomes promote intestinal epithelial cell growth
Breast milk administration prevents necrotizing enterocolitis (NEC). However, the mechanism remains unclear. Exosomes are cell-derived vesicles highly present in human milk and regulate intercellular signaling, inflammation, and immune response. Researchers from The Hospital for Sick Children hypothesized that milk-derived exosomes ...
Read More »Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assay
Extracellular vesicles (EVs) are membrane-coated objects such as exosomes and microvesicles, released by many cell-types. Their presence in body fluids and the variable surface composition and content render them attractive potential biomarkers. The ability to determine their cellular origin could ...
Read More »Exosomes in Human Breast Milk Promote EMT
Pregnancy increases breast cancer risk for all women for at least 5 years after parturition. During weaning and involution the breast microenvironment becomes tumor promotional. Exosomes provide cell-cell communication during physiologic processes such as lactation, but also in breast cancer. ...
Read More »Exosomes – A Major Phenomenon Flying Under the Radar
from The Cell Culture Dish – A guest blog by William G. Whitford, Strategic Solutions Leader, BioProcess, GE Healthcare Life Sciences Exosomes in Nature It was discovered some time ago that eukaryotic cells regularly secrete such structures as microvesicles, macromolecular ...
Read More »Functions and application of exosomes
The cells continuously secrete a large number of different types of microvesicles including macro-and micro-molecules into the extracellular fluids. One of them are exosomes, which are nano-sized vesicles capable of transferring the DNAs, microRNAs, non-coding RNAs and lipids with or ...
Read More »Recovery of extracellular vesicles from human breast milk is influenced by sample collection and vesicle isolation procedures
Extracellular vesicles (EV) in breast milk carry immune relevant proteins and could play an important role in the instruction of the neonatal immune system. To further analyze these EV and to elucidate their function it is important that native populations ...
Read More »Secreated Extracellular Vesicles
from abcam.com Various secreted extracellular vesicles are present in urine, amniotic fluid, bronchoalveolar lavage fluid, breast milk, saliva and blood
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