Circulating microRNAs carried by exosomes have emerged as promising diagnostic biomarkers for cancer because of their abundant amount and remarkable stability in body fluids. Exosomal microRNAs in...
Read More »Exosomes as a Multicomponent Biomarker Platform in Cancer
Cancer is a complex disease that is associated with genetic aberrations and subsequent cellular and noncellular host responses. Tumors harbor diverse cell types that engage in a dynamic interplay to sustain cancer-specific signaling networks. A component of such cellular communication ...
Read More »Electrochemical immunosensing of nanovesicles as biomarkers for breast cancer
Exosomes are nano-sized vesicles, which are currently under intensive study as potential diagnostic biomarkers for many health disorders, including cancer. Researchers from UAB Barcelona tested an electrochemical immunosensor in different formats for the characterization and quantification of exosomes derived from ...
Read More »Emerging Function and Clinical Values of Exosomal MicroRNAs in Cancer
Exosomes are a subset of membrane-bound extracellular vesicles with diameters ranging from 30 to 100 nm. Exosomes enclose a variety of molecules...
Read More »The role of pancreatic cancer-derived exosomes in cancer progress and their potential application as biomarkers
Pancreatic cancer is one of the most deadly cancers, with dismal prognosis due to its poor early detection rate and high metastatic rate. Thus, elucidation of the molecular mechanisms accounting for its metastasis and discovery of competent biomarkers is required. ...
Read More »New Patent Published – miRNA biogenesis in exosomes for diagnosis and therapy
Kalluri, Raghu (Houston, TX, US) Melo, Sónia (Porto, PT) Abstract The presently disclosed subject matter provides methods of diagnosis of cancer or adverse pregnancy outcomes in a subject by measuring amounts of one or more microRNAs present in cancer-derived exosomes ...
Read More »Exosomes as Biomarkers for Brain Tumors
Xandra O. Breakefield Massachusetts General Hospital Cancer Center Harvard Medical School
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