The structure and size of exosomes are not too different from the key player of the COVID-19...
Read More »Rapid Isolation and Detection of Exosomes and Associated Biomarkers from Plasma
Exosomes found in the circulation are a primary source of important cancer-related RNA and protein biomarkers that are expected to lead to early detection, liquid biopsy, and point-of-care diagnostic applications. Unfortunately, due to their small size (50-150 nm) and low ...
Read More »Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assay
Extracellular vesicles (EVs) are membrane-coated objects such as exosomes and microvesicles, released by many cell-types. Their presence in body fluids and the variable surface composition and content render them attractive potential biomarkers. The ability to determine their cellular origin could ...
Read More »Separation of different miRNA carriers in human serum with asymmetrical flow field flow fractionation (AF4)
MicroRNAs (miRNAs) are stably present in circulatory systems. They are bound to various carriers like proteins, lipoprotein particles, and exosomes. Investigating the process of miRNA distribution among these carriers will help improve our understanding of their functions in the extracellular ...
Read More »Exosomes serve as tumour markers for personalized diagnostics
Exosomes, membrane vesicles of 40-100 nm in diameter, are derived from endosomes in various cells. The bioactive molecules specifically packed into exosomes can be horizontally transferred into recipient cells changing their biological properties, by which tumour cells continuously modify their ...
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