Researchers used high-speed atomic force microscopy to measure antibody binding to PD-L1 on individual extracellular vesicles, revealing differences in protein accessibility that conventional measurements may miss...
Read More »Clinical trial to evaluate blood test for early detection of breast cancer
USC researchers are evaluating a blood test that detects tumor-associated extracellular vesicles and rare cancer cells, potentially improving early breast cancer detection alongside mammography...
Read More »iEVIP: a dual-inspired intelligent platform for smart response extracellular vesicle isolation and single-vesicle profiling
Extracellular vesicles are isolated and profiled with iEVIP, combining responsive filtration, single-vesicle imaging, and machine learning for exploratory cancer-related sample classification...
Read More »Electrical fingerprint on tiny cell particles could offer new way to spot pancreatic cancer signals
Extracellular vesicles from pancreatic cancer patients show distinct electrical properties linked to KRAS activity, offering a potential new approach for enriching cancer-associated biomarkers...
Read More »Extracellular vesicle integrins show potential for detecting early breast cancer and bone metastasis
Plasma extracellular vesicles carrying integrins αV and β3 show potential as biomarkers for early breast cancer detection and identifying disease associated..
Read More »DNA barcoding separates extracellular vesicle subpopulations for gastric cancer detection
DNA barcoding separates extracellular vesicles into tumor-associated subpopulations, enabling miRNA profiling that may improve liquid biopsy detection...
Read More »Ultrasensitive biosensor detects extracellular vesicles for potential cancer screening
An ultrasensitive electrochemical biosensor detects low-abundance extracellular vesicles in serum, demonstrating potential for rapid, minimally...
Read More »Exosome proteins and microRNAs reveal shared patterns across cancers
Integrated profiling of proteins and microRNAs in cancer-derived exosomes reveals shared biological functions and cancer-specific patterns with...
Read More »Tiny bacterial vesicles could help shape precision cancer treatment
Bacterial extracellular vesicles offer a versatile platform for targeted drug delivery, immunotherapy, cancer vaccines, biomarker discovery, and tumor monitoring in precision oncology...
Read More »New study explores collection of extracellular vesicles to aid cancer diagnosis
Extracellular vesicles isolated from patient blood using size-exclusion chromatography show potential for cancer diagnosis, clinical assessment, and...
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