Researchers used high-speed atomic force microscopy to measure antibody binding to PD-L1 on individual extracellular vesicles, revealing differences in protein accessibility that conventional measurements may miss...
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Engineered extracellular vesicles may improve mRNA cancer vaccine delivery while supporting targeted immune responses, tumor microenvironment remodeling, and personalized neoantigen-based...
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Spatial-EV-seq maps extracellular vesicles within intact tissues, revealing how their location and movement can shape immune activity and cellular communication in the tumor microenvironment...
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Cancer-mimicking exosomes provide nanovials with more natural antigen presentation, improving therapeutic T cell capture and activation for high...
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Bacterial extracellular vesicles offer a versatile platform for targeted drug delivery, immunotherapy, cancer vaccines, biomarker discovery, and tumor monitoring in precision oncology...
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Engineered extracellular vesicles precisely reprogram tumor-associated macrophages, boosting anti-tumor immunity and phagocytosis while suppressing tumor growth and metastasis in preclinical models...
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Extracellular vesicles can be reprogrammed to stimulate anticancer immunity, offering a new strategy to improve immunotherapy and reduce...
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Spatial-EV-seq combines extracellular vesicles with transcriptomics to map EV-cell communication directly within tissues, providing new opportunities for precision diagnostics and cancer research....
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Therapeutic poxviruses stimulate extracellular vesicles carrying viral antigens and immune activators, producing strong antitumor responses and revealing a new mechanism supporting cancer immunotherapy...
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Extracellular vesicles released by activated T cells transferred DNA to immune and tumor cells, enhancing antigen presentation and strengthening anti-tumor immune responses...
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