The highlights of cancer research include the discovery of exosomes, which are small (30-100 nm) sized vesicular nanoparticles released virtually by all cells. Tumor-derived exosomes (TDEs) are notoriously known for orchestrating the invasion-metastasis cascade via systemic pathways...
Read More »Breast Cancer-Derived Extracellular Vesicles
The study of extracellular vesicles (EVs) in cancer progression is a complex and rapidly evolving field. Whole categories of cellular interactions in cancer which were originally presumed to be due solely to soluble secreted molecules have now evolved to include ...
Read More »Exosome proteins predict cancer’s spread
from the Cornell Chronicle By Alla Katsnelson It’s been a long-standing mystery why certain types of cancers spread to particular organs in the body. Now, investigators at Weill Cornell Medicine have discovered precisely how this happens, supporting a century-old hypothesis ...
Read More »A review of exosome separation techniques
Exosomes participate in cancer metastasis, but studying them presents unique challenges as a result of their small size and purification difficulties. Asymmetrical field flow fractionation with in-line ultraviolet absorbance, dynamic light scattering, and multi-angle light scattering was applied to the ...
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