Researchers at the Shin-Yamanote Hospital, Japan transfected B16 melanoma cells with a plasmid encoding the M. tuberculosis antigen, early secretory antigenic target-6 (ESAT-6). The secreted exosomes bearing both tumor-associated antigens and the pathogenic antigen (or their epitopes) were collected. When ...
Read More »Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC
Dendritic cell-derived exosomes (Dex) are small extracellular vesicles secreted by viable dendritic cells. In the two phase-I trials conducted using the first generation of Dex (IFN-γ-free) in end-stage cancer, a team led by researchers at Paris-Sud University, reported that Dex ...
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