Cancer-derived circulating exosomes or nanoscale extracellular vesicles are emerging biomarkers for disease detection and treatment because of their cell-specific constituents and unique intercellular...
Read More »Microfluidic human liver-chip to investigate the roles of breast cancer-derived extracellular vesicles
A new study, affiliated with UNIST has unveiled the mechanisms involved in the liver metastasis of breast cancer, thanks to the three-dimensional (3D) organ-on-a-chip that mimics human liver functions...
Read More »Extracellular RNAs as potential biomarkers for cancer
The discovery that all cells secrete extracellular vesicles (EVs) to shuttle proteins and nucleic acids to recipient cells suggested they play an important role in intercellular communication. EVs are widely distributed in many body fluids, including blood, cerebrospinal fluid, urine ...
Read More »Emerging roles of exosomal circular RNAs in cancer
Circular RNA (circRNA) is a type of non-coding RNA that forms a covalently closed continuous loop. The expression pattern of circRNA varies among cell types and tissues, and many circRNAs are aberrantly expressed in various cancers. Aberrantly expressed circRNAs have ...
Read More »miR Scientific announces FDA breakthrough device designation for its prostate cancer liquid biopsy test
miR Scientific, LLC, a healthcare company whose purpose is to transform global cancer management by providing early and highly accurate detection, characterization and monitoring of disease, announced...
Read More »Emerging prospects of exosomes for cancer treatment
Exosomes are a class of extracellular vesicles of around 100 nm in diameter that are secreted by most cells and contain various bioactive molecules reflecting their cellular origin and mediate intercellular communication. Studies of these exosomal features in tumor pathogenesis ...
Read More »Illumina to pay $8B to reacquire cancer blood test maker Grail
Illumina, Inc. and GRAIL, a healthcare company whose mission is focused on multi-cancer early detection, today announced they have entered into a definitive agreement under which Illumina will...
Read More »Hybrid nanoplasmonic porous biomaterial scaffold for liquid biopsy diagnostics using extracellular vesicles
For more effective early-stage cancer diagnostics, there is a need to develop sensitive and specific, non- or minimally invasive, and cost-effective methods for identifying circulating nanoscale extracellular...
Read More »First engineered exosome for the treatment of cancer enters clinical development
Codiak BioSciences, a clinical-stage company focused on pioneering the development of exosome-based therapeutics as a new class of medicines...
Read More »A facile, rapid, high-throughput extracellular vesicles analytical platform for cancer detection
Cell-derived nanoparticles, so called Extracellular Vesicles (EVs), can reflect the physiological or pathological conditions of donor cells and can provide promising biomarkers for the non-invasive diagnosis of cancers. Size-based purification method is one of the common strategies for rapid extracting ...
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