Capricor Therapeutics, Inc. a clinical-stage biotechnology company developing biological therapies for cardiac and other serious medical conditions, today announced that the U.S. Department of Defense (DoD) has awarded the company a grant1 in the amount of approximately $2.4 million to ...
Read More »Cardiac Exosome Modeling and Therapy
To regenerate heart tissue after a myocardial infarction, researchers have investigated cell therapies involving cardiac progenitor cells. These cells can differentiate into heart cells such as cardiac myocytes, endothelial cells and fibroblasts, but it is not clear whether this differentiation ...
Read More »Microvesicles and exosomes for intracardiac communication
The heart is an organ with a complex mixture of well-organized interactions of different cell types that facilitate proper myocardial contractility, sufficient perfusion, balanced myocardial extracellular stiffness, and controlled functioning of the immune system. Several cell types, including cardiomyocytes, endothelial ...
Read More »The role of exosomes in myocardial remodeling
Exosomes are nanovesicles released from cells through exocytosis and are known to be mediators of proximal as well as distant cell-to-cell signaling. They are surrounded by a classical bilayered membrane with an exceptionally high cholesterol/phospholipid ratio. Exosomes were first described ...
Read More »