The development of a new technique for labelling the body’s own transporters – exosomes – could have long term benefits in the treatment of life-threatening medical conditions, including cancer. A team of researchers at Cardiff University’s Schools of Pharmacy and ...
Read More »PhD in Cell Biology – The role of heparan sulphate proteoglycans in exosome-mediated growth factor delivery & prostate tumour growth
ORGANISATION/COMPANY – Cardiff University RESEARCH FIELD – Biological sciences – Medical sciences RESEARCHER PROFILE – First Stage Researcher (R1) APPLICATION DEADLINE – 28/02/2017 17:00 – Europe/London This is a full time, 3-year, PhD project funded by Cancer Research Wales, and ...
Read More »Extracellular vesicle production is higher in cells before adipogenesis
Extracellular vesicles (EVs) are submicron vesicles released from many cell types, including adipocytes. EVs are implicated in the pathogenesis of obesity-driven cardiovascular disease, although the characteristics of adipocyte-derived EVs are not well described. Researchers at Cardiff University sought to define ...
Read More »Ready-made chromatography columns for extracellular vesicle isolation from plasma
Proteomic studies of circulating vesicles are hampered by difficulties in purifying vesicles from plasma and serum. Isolations are contaminated with high-abundance blood proteins that may mask genuine vesicular-associated proteins and/or simply provide misleading data. In this brief report, we explored ...
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