Four of six critically ill COVID-19 (coronavirus) patients significantly improved after receiving an experimental therapeutic designed to reduce inflammation, a major cause of death from this...
Read More »CDC-generated exosomes improve function in Duchenne muscular dystrophy
A stem cell therapy improved the heart function, walking capacity and survival of mice with Duchenne muscular dystrophy, a study reports. The treatment involves what scientists call cardiosphere-derived cells, or CDCs. They are the research equivalent of the stem cell therapy ...
Read More »A comprehensive method for identification of suitable reference genes in extracellular vesicles
Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) is one of the most sensitive, economical and widely used methods for evaluating gene expression. However, the utility of this method continues to be undermined by a number of challenges including normalization using appropriate ...
Read More »Cardiac cell-derived exosomes are changing face of regenerative biology
Naturally secreted nanovesicles known as exosomes are required for the regenerative effects of cardiosphere-derived cells (CDCs), and exosomes mimic the benefits of CDCs in rodents. Nevertheless, exosomes have not been studied in a translationally realistic large-animal model. Researchers from Cedars-Sinai ...
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