Cardiovascular diseases (CVDs) continue to represent the number one cause of death and disability in industrialized countries. The most severe form of CVD is acute myocardial infarction (AMI), a devastating disease associated with high mortality...
Read More »Exosomes – A Rising Star in Falling Hearts
Although exosomes were previously recognized as a mechanism for discharging useless cellular components, growing evidence has elucidated their roles in conveying information between cells. They contribute to cell-cell communication by carrying nucleic acids, proteins and lipids that can, in turn, ...
Read More »Methodological Guidelines to Study Extracellular Vesicles
All body fluids contain cell-derived membrane-enclosed vesicles. Such vesicles are shed by prokaryotes and eukaryotic cells and contain messages to the environment. Cell-derived vesicles are thought to contribute to homeostasis, disease development, and progression, may provide novel biomarkers, and may ...
Read More »Exosome Drug Developer Capricor Therapeutics Inc (CAPR) is Initiated by ROTH Capital to Buy
from The Market Digest by Robert Westfall Capricor Therapeutics Inc (CAPR) was Initiated by ROTH Capital to “Buy”. ROTH Capital advised their investors in a research report released on Jun 15, 2016. Capricor Therapeutics Inc opened for trading at $3.31 ...
Read More »Stem Cell Exosomes for Cardiac Repair
Stem cell therapy provides immense hope for regenerating the pathological heart, yet has been marred by issues surrounding the effectiveness, unclear mechanisms, and survival of the donated cell population in the ischemic myocardial milieu. Poor survival and engraftment coupled to ...
Read More »SHPERE Study – Susceptibility to particle health effects, miRNA and exosomes
Despite epidemiological findings showing increased air pollution related cardiovascular diseases (CVD), the knowledge of the involved molecular mechanisms remains moderate or weak. Particulate matter (PM) produces a local strong inflammatory reaction in the pulmonary environment but there is no final ...
Read More »Extracellular vesicles as therapeutic tools in cardiovascular diseases
Extracellular vesicles (EVs), including microvesicles (MVs) and exosomes, are small vesicles secreted from a wide variety of cells. Whereas MVs are particles released by the outward budding of the plasma membrane, exosomes are derived from endocytic compartments. Secretion of EVs ...
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