Four of six critically ill COVID-19 (coronavirus) patients significantly improved after receiving an experimental therapeutic designed to reduce inflammation, a major cause of death from this...
Read More »NUI Galway has launched a new €7.45 million project for robotic production of regenerative stem cell therapies for osteoarthritis
NUI Galway’s Regenerative Medicine Institute has launched a new €7.45 million project to develop ground-breaking and innovative scientific and engineering platforms for the production of advanced...
Read More »Cell-based and exosome therapy in diabetic stroke
Stroke is a global health concern and it is imperative that therapeutic strategies with wide treatment time frames be developed to improve neurological outcome in patients. Patients with diabetes mellitus who suffer a stroke have worse neurological outcomes and long-term ...
Read More »Mesenchymal stem/stromal cell-derived extracellular vesicles have clinical potential
Within the last two decades mesenchymal stem/stromal cells (MSCs) emerged after hematopoietic stem cells as the second most investigated and applied somatic stem cell entity so far. MSCs mediate immunosuppressive as well as pro-regenerative activities. Against the initial assumption, MSCs ...
Read More »Emerging potential of exosomes for treatment of traumatic brain injury
Traumatic brain injury (TBI) is one of the major causes of death and disability worldwide. No effective treatment has been identified from clinical trials. Compelling evidence exists that treatment with mesenchymal stem cells (MSCs) exerts a substantial therapeutic effect after ...
Read More »Stem Cell Exosomes – Cell-FreeTherapy for Organ Repair
Cardiovascular disease is a significant cause of morbidity and mortality around the world. The damaged cardiac tissue is unable to repair itself following injury warranting the development of alternate therapies. Cell therapy has emerged recently as a viable treatment option ...
Read More »Commercialisation Opportunity – Exosome Therapy – a cell-free approach to regenerative medicine
Background: What’s an Exosome? Exosomes are nanosizedvesicles released by all cell types, including stem cells. Exosomes contain ‘cargo’ such as proteins, RNA and cytokines which reflect the intracellular contents of their donor cell. DrLim, and others, have found that exosome ...
Read More »Can exosomes be used as a cell-based immune therapy against HIV-I?
Dendritic cell (DC)-based immune therapy (IT) against HIV showed variable results. It is known that different factors influence host response to DC-IT. Exosomes derived from DC are regulators of the immune system. In this context, here researchers from the Federal ...
Read More »Cardiac cell-derived exosomes – the holy grail of cardiac medicine
Repair of the damaged cardiac tissue has been considered the holy grail of cardiac medicine driving researchers for years. Myocardial damage in an adult heart leads to widespread cardiomyocyte loss without active replacement of the dead cardiac tissue, ultimately resulting ...
Read More »Cells talk to each other, but do members of the scientific community communicate with each other?
Do molecular and cellular biologists speak with clinicians? In the last few years, numerous research centers have been located close to hospitals leading toward a more fluid connection between clinical and basic researchers, and therefore, translational medicine is becoming increasingly ...
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