Izon Science announces the release and immediate availability of its new analytical-scale exosome isolation column, the qEVsingle. Based on Size Exclusion Chromatography, the qEVsingle is designed to handle 100μL samples of biological fluids (blood plasma or serum, CSF, saliva, urine, ...
Read More »Purification of virus-like particles and separation of other extracellular particles
Enveloped virus-like particles (VLPs) are increasingly used as vaccines and immunotherapeutics. Frequently, very time consuming density gradient centrifugation techniques are used for purification of VLPs. However, the progress towards optimized large-scale VLP production increased the demand for fast, cost efficient ...
Read More »Ready-made chromatography columns for extracellular vesicle isolation from plasma
Proteomic studies of circulating vesicles are hampered by difficulties in purifying vesicles from plasma and serum. Isolations are contaminated with high-abundance blood proteins that may mask genuine vesicular-associated proteins and/or simply provide misleading data. In this brief report, we explored ...
Read More »Methods of isolating extracellular vesicles impact down-stream analyses of their cargoes
Viable tumor cells actively release vesicles into the peripheral circulation and other biologic fluids, which exhibit proteins and RNAs characteristic of that cell. Researchers from Exosome Sciences, Inc demonstrated the presence of these extracellular vesicles of tumor origin within the peripheral ...
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