Extracellular vesicles and ciliary signaling in C. elegans help reveal how an ADPKD-associated mutation disrupts polycystin protein localization...
Read More »Discovery of new ciliary proteins suggests link between cell antennae and chronic diseases
Researchers at the University of Copenhagen discovered two new ciliary proteins linked to diabetes, obesity, and kidney disease, revealing how extracellular vesicles regulate cell communication and may influence disease development...
Read More »The exocyst complex is centrally involved in “urocrine signaling”
Cilia, organelles that function as cellular antennae, are central to the pathogenesis of “ciliopathies”, including various forms of polycystic kidney disease (PKD). To date, however, the molecular mechanisms controlling ciliogenesis and ciliary function remain incompletely understood. A recently proposed model ...
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